Results 31 to 40 of about 1,592,983 (303)
Role of Yes-associated protein in cancer: An update
Oncology Letters, 2016 Yes-associated protein (YAP) is an oncoprotein located in the cytoplasm in an inactive form, and when activated, it translocates to the nucleus and activates the transcription of genes responsible for cell division and apoptosis. YAP is one of the downstream regulatory proteins in the Hippo signaling pathway, which is important in cell proliferation ...
Abylkassov, Ramazan, Xie, Yingqiu
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Role of Yes-Associated Protein in Psoriasis and Skin Tumor Pathogenesis
Journal of Personalized Medicine, 2022 Psoriasis and skin tumors (such as basal cell carcinoma, squamous cell carcinoma, and melanoma) are chronic diseases that endanger physical and mental health, and yet the causes are largely unknown and treatment options limited. The development of targeted drugs requires a better understanding of the exact pathogenesis of these diseases, and Yes ...
Jinjing Jia +3 more
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Yes-Associated Protein is Involved in Myocardial Fibrosis in Rats with Diabetic Cardiomyopathy
Diabetes, Metabolic Syndrome and Obesity, 2021 Maomao Hu,1,2,* Han Wang,1– 3,* Shengnan Li,1,2,* Feng Yan,2 Changning Fu,1,2 Lei Li,1,2 Yalin Yu,1,2,4 Jie Xiong,1,2 Bo Dong1,2,4 1Department of Cardiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250012, People ...
Hu M +8 more
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Pharmaceutical Biology, 2020 Context Emodin is a compound in Rheum undulatum Linne (Polygonaceae) that has been reported to exert anti-inflammatory, antibacterial, and antiallergic effects.
Eun Hye Lee +3 more
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Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]
, 2017 The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca +12 more
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Frontiers in Cellular and Infection Microbiology, 2016 Gram-negative bacterial lipopolysaccharide (LPS) induces a pathologic increase in lung vascular leakage under septic conditions. LPS-induced human pulmonary micro-vascular endothelial cell (HPMEC) apoptosis launches and aggravates micro-vascular hyper ...
Lei Yi +6 more
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Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells [PDF]
, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Cantatore, Francesco P +5 more
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Tumor Biology, 2017 Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments.
Honglong Wei +6 more
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Biomedicines, 2022 Pregnancy morbidity induced by anti-phospholipid antibodies (aPL+/PM+) is mainly thought to arise from placental abnormalities. We attempted to investigate the effect of aPL on the activity of Yes-associated protein (YAP) in the trophoblast and how YAP ...
Zengshu Huang +6 more
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Yes-associated protein 1 regulates the stability of ΔNp63α [PDF]
Cell Cycle, 2010 Regulation of ΔNp63α can be achieved at the transcriptional and post-translational levels, with the latter being greatly influenced by external stimuli such as DNA damaging agents. In this present study, we demonstrated that ΔNp63α physical interacts with Yes-associated protein 1 (Yap1).
Aditi Chatterjee +3 more
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