Results 1 to 10 of about 14,124 (155)

A literature perspective on the pharmacological applications of yohimbine

Annals of Medicine, 2022
Introduction: Phytochemicals have garnered much attention because they are useful in managing several human diseases. Yohimbine is one such phytochemical with significant pharmacological potential and could be exploited for research by medicinal chemists.
Nasimudeen R Jabir, Mohd Khan, Shams Tabrez   +2 more
exaly   +3 more sources

Unveiling bioactive compounds in kola nut seeds: GC-MS identification and computational analysis for anticancer potential [PDF]

Frontiers in Nutrition
IntroductionCancer continues to pose a critical global health challenge, with conventional therapies often limited by efficacy and adverse side effects.
Azzah Alshehri, Azzah Alshehri, Azzah Alshehri, Saleh Bahaffi, Mohd Rehan, Mohd Rehan, Mohd Suhail, Mohd Suhail, Ahmed I. Al-Asmari, Ahmed I. Al-Asmari, Diaa T. A. Youssef, Diaa T. A. Youssef, Alaa Khedr, Alaa Khedr, Torki Zughaibi, Torki Zughaibi   +15 more
doaj   +2 more sources

Scientific Opinion on the evaluation of the safety in use of Yohimbe (Pausinystalia yohimbe (K. Schum.) Pierre ex Beille) [PDF]

EFSA Journal, 2013
The Panel on Food Additives and Nutrient Sources added to Food provides a scientific opinion evaluating the safety in use of yohimbe bark and its preparations originating from Yohimbe (Pausinystalia yohimbe (K. Schum.) Pierre ex Beille when used in food,
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
doaj   +3 more sources

Berberine ameliorates acute hyperglycemia and hypoinsulinemia induced by ketamine/xylazine in rats: role of alpha2 adrenergic receptors, oxidative stress and inflammatory suppressing mechanisms [PDF]

BMC Veterinary Research
Background Xylazine is a common veterinary drug used for sedation, anesthesia, muscle relaxation and analgesia. Berberine (C20H18NO4 +) is an alkaloid compound found in different plant species with a wide range of biological and pharmacological ...
Rusul Abdulhameed Kadhim, Amir Erfanparast, Esmaeal Tamaddonfard, Davoud Amirkashani, Mehdi Imani   +4 more
doaj   +2 more sources

Oxytocin Reduces Noradrenergic-Induced Opioid-Like Withdrawal Symptoms in Individuals on Opioid Agonist Therapy [PDF]

Biological Psychiatry Global Open Science
Background: Intranasal administration of the neuropeptide oxytocin has been explored as a potential therapeutic agent for substance use disorder including opioid use disorder (OUD).
Brian J. Gully, Zoe E. Brown, Rivkah Hornbacher, Joshua C. Brown, Sudie E. Back, Elinore F. McCance-Katz, Robert M. Swift, Carolina L. Haass-Koffler   +7 more
doaj   +2 more sources

Basal cortisol level modulates stress-induced opioid-seeking behavior [PDF]

Neurobiology of Stress
In preclinical studies and our human laboratory, the α2-noradrenergic autoreceptor antagonist yohimbine was found to promote drug-seeking behavior. This study evaluated effects of dose-combinations of yohimbine and the glucocorticoid receptor agonist ...
Mark K. Greenwald, Eric A. Woodcock, Tabitha E.H. Moses, Leslie H. Lundahl   +3 more
doaj   +2 more sources

Comparative efficacy of yohimbine and tolazoline for antagonism of ketamine-xylazine induced sedation in captive wild felids [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021
This study was conducted to investigate the comparative efficacy of yohimbine and tolazoline for antagonism of ketamine-xylazine induced sedation in captive wild felids in Pakistan.
Ameer Hamza RABBANI, Yasir Razzaq KHAN, Omer NASEER, Kashif HUSSEIN, Ahmad ALI, Abdul WAHEED, Muhammad SHAHID, Hareem AFZAL   +7 more
doaj   +3 more sources

Inhibition of α2-adrenoceptor is renoprotective in 5/6 nephrectomy-induced chronic kidney injury rats

Journal of Pharmacological Sciences, 2021
In the present study, we investigated the renoprotective effects of long-term treatment with yohimbine, an α2-adrenoceptor inhibitor, in a 5/6 nephrectomy-induced chronic kidney disease (CKD) rat model.
Kohei Hayashi, Takaomi Shimokawa, Masayo Yamagata, Kozo Yoneda   +3 more
doaj   +1 more source

Yohimbine as a treatment for erectile dysfunction: A systematic review and meta-analysis

Urology Research and Practice, 2021
In recent years, several studies have reported promising results of Yohimbine as a natural supplement for erectile dysfunction (ED). However, several studies suggested that the aphrodisiac effects of the extract were only a placebo or due to the increase
Dwi Nanda Satriyo Arif Wibowo, Doddy Moesbadianto Soebadi, Mohammad Ayodhia Soebadi   +2 more
doaj   +1 more source

Successful reversal of a rare case of amitraz poisoning with yohimbine—a case report

Ain Shams Journal of Anesthesiology, 2022
Background Amitraz is an insecticidal agent and its poisoning cases are rare. We report the successful treatment of amitraz poisoning using yohimbine as an antidote. There is only a single other case report in literature of usage of yohimbine as antidote
Ankur Gupta, Achint Narang, Nikhil Shandilya, Aman Sharma, Rahul Kathuria, Aakriti Gupta   +5 more
doaj   +1 more source