Results 21 to 30 of about 6,560 (173)

Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments

open access: yesCurrent Issues in Molecular Biology, 2021
The use of pharmaceuticals to treat Major Depressive Disorder (MDD) has several drawbacks, including severe side effects. Natural compounds with great efficacy and few side effects are in high demand due to the global rise in MDD and ineffective ...
Munazzah Tasleem   +7 more
doaj   +1 more source

Combined In Vivo Microdialysis and PET Studies to Validate [11C]Yohimbine Binding as a Marker of Noradrenaline Release

open access: yesBiomolecules, 2023
The noradrenaline system attracts attention for its role in mood disorders and neurodegenerative diseases but the lack of well-validated methods impairs our understanding when assessing its function and release in vivo.
Anne Marlene Landau   +9 more
doaj   +1 more source

Oxytocin Attenuates Yohimbine-Induced Reinstatement of Alcohol-Seeking in Female Rats via the Central Amygdala

open access: yesBehavioral Sciences, 2023
Alcohol use disorder is a significant public health concern, further exacerbated by an increased risk of relapse due to stress. In addition, factors such as biological sex may contribute to the progression of addiction, as females are especially ...
Samantha M. Wilfur   +4 more
doaj   +1 more source

Oxytocin Attenuates the Stress-Induced Reinstatement of Alcohol-Seeking in Male Rats: Role of the Central Amygdala

open access: yesBiomedicines, 2021
Factors such as stress and anxiety often contribute to alcohol-dependent behavior and can trigger a relapse of alcohol addiction and use. Therefore, it is important to investigate potential pharmacological interventions that may alleviate the influence ...
Hannah S. Ballas   +3 more
doaj   +1 more source

Scientific Opinion on the evaluation of the safety in use of Yohimbe (Pausinystalia yohimbe (K. Schum.) Pierre ex Beille) [PDF]

open access: yesEFSA Journal, 2013
The Panel on Food Additives and Nutrient Sources added to Food provides a scientific opinion evaluating the safety in use of yohimbe bark and its preparations originating from Yohimbe (Pausinystalia yohimbe (K. Schum.) Pierre ex Beille when used in food,
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
doaj   +1 more source

Possible Protective Effects of Omega 3, Diazepam and their Combination Against Yohimbine-Induced Clonic Seizure in Mice: Comparative Study

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
Yohimbine is actually confirmed in the United States to be utilized for erectile dysfunction; and recently such drug has become commonly used in body-building communities for its presumed lipolytic and sympathomimetic effects.
Manal Abdulkhaliq Ibrahim   +2 more
doaj   +1 more source

The effect of alpha-2 adrenergic receptors on memory retention deficit induced by rapid eye movement sleep deprivation [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Evidence shows that sleep deprivation (SD) disrupts the formation of hippocampus-related memories. Moreover, α2 adrenergic receptors that are wildly expressed in the CA1 hippocampal region have a significant role in modulating both sleep ...
Yaser Norozpour   +5 more
doaj   +1 more source

The Role of Central Catecholaminergic Systems in Regulation of Food Intake of Chicks

open access: yesThe Journal of Poultry Science, 2001
To clarify catecholaminergic systems on the regulation of food intake in the neonatal chick, we examined the effects of intracerebroventricular (ICV) injection of prazosin (α1-adrenoceptor antagonist), yohimbine (α2-adrenoceptor antagonist ...
Takashi Bungo   +4 more
doaj   +1 more source

Locus coeruleus inhibition of vibrissal responses in the trigeminal subnucleus caudalis are reduced in a diabetic mouse model

open access: yesFrontiers in Cellular Neuroscience, 2023
Diabetic neuropathy is the loss of sensory function beginning distally in the lower extremities, which is also characterized by pain and substantial morbidity.
Alberto Mesa-Lombardo   +3 more
doaj   +1 more source

A Fast and Reliable UHPLC–MS/MS-Based Method for Screening Selected Pharmacologically Significant Natural Plant Indole Alkaloids

open access: yesMolecules, 2020
Many substances of secondary plant metabolism have often attracted the attention of scientists and the public because they have certain beneficial effects on human health, although the reason for their biosynthesis in the plant remains unclear.
Danuše Tarkowská
doaj   +1 more source

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