Frontiers in Aging Neuroscience, 2022 Background: Inflammation promotes the progression of Alzheimer’s disease (AD). In this study, we explored the effect of dexmedetomidine on inflammation and cognitive function in a mouse model of AD.Methods: 5xFAD mice were intragastrically administered ...
Su-mei Luo +8 more
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Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating [PDF]
, 2011 Sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. We investigated whether this diminished response was due to altered contributions of noradrenergic sympathetic nerves; assessing 1) the age-related decline and,
Alan D. Ruddock +6 more
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Yohimbine is a 5-HT1A agonist in rats in doses exceeding 1 mg/kg. [PDF]
, 2015 Yohimbine is a prototypical alpha2-adrenergic receptor antagonist. Due to its relatively high selectivity, yohimbine is often used in experiments whose purpose is to examine the role of these receptors.
DiMicco, Joseph A. +3 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Cardiovascular diseases are the most common human diseases, hence, the production of cardiological (in particular, anti-arrhythmic) medications from the natural sources is an ever-actual task. Rauwolfia serpentina Benth.
O. A. Bieda +5 more
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Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]
, 2004 Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C. +2 more
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Heliyon, 2021 In order to optimize the survival rate of animals, the purpose of this study was to evaluate an injectable anesthesia protocol for the development of a murine model of hepatic cystic echinococcosis in female CF-1 mice.
Nathalia P. Scioscia +3 more
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State-Dependent Subnetworks of Parvalbumin-Expressing Interneurons in Neocortex. [PDF]
, 2019 Brain state determines patterns of spiking output that underlie behavior. In neocortex, brain state is reflected in the spontaneous activity of the network, which is regulated in part by neuromodulatory input from the brain stem and by local inhibition ...
Garcia-Junco-Clemente, Pablo +3 more
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Effect of Curcumin, an Active Substance of Turmeric, on Acute Hyperglycemia Induced by Ketamine-Xylazine: Role of α2-Adrenergic Receptor [PDF]
Iranian Journal of Veterinary Surgery, 2020 Objective- Medicinal plants and their active constituents are frequently used components for treating hyperglycemia. In the present study, the effect of curcumin was investigated on acute hyperglycemia and hyperinsulinemia induced by ketamine-xylazine in
Esmaeal Tamaddonfard +4 more
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New-Onset Psychosis in a Person with Parkinson's Disease after "Horny Goat Weed" Use. [PDF]
Mov Disord Clin PractMovement Disorders Clinical Practice, Volume 13, Issue 2, Page 541-543, February 2026.
Deliz JR +3 more
europepmc +2 more sources
EFFECTS OF YOHIMBINE ON PLASMA LEVELS OF LEPTIN IN NORMAL AND STREPTOZOTOCIN INDUCED DIABETIC RATS [PDF]
Acta Medica Iranica, 2006 Leptin affects paraventricular nucleus of hypothalamus and reduces appetite while activation of α2-adrenoceptors at this site has opposite action.
M. Mohammadi Naghadeh +2 more
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