Results 131 to 140 of about 7,941 (215)

Enterovirus 71 structural viral protein 1 promotes the expression of PMP22 through m6A modification in mouse Schwann cells

Virus Research
Purpose: Enterovirus 71 (EV71) is one of the enteroviruses that causes hand-foot-and-mouth disease (HFMD). This study aims to investigate the role of EV71 structural viral protein 1 (VP1) in mouse Schwann cells. Methods: An EV71 VP1-expressing vector was
Qiuyan Peng, Guangming Liu, Danping Zhu, Suyun Li, Sida Yang, Peiqing Li, Yingxian Yin, Dandan Hu   +7 more
doaj   +1 more source

YTHDF1 activates FBW7 transcription by regulating m6A-dependent FOXO1 to facilitate inflammatory response in ulcerative colitis-like model

Autoimmunity
The prevalence of inflammatory bowel disease (IBD) has increased recently and lacks curative treatments. The involvement of the N6-methyladenosine (m6A) reader YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) in ulcerative colitis (UC)-like model ...
Hui Zhang, Meili Xu
doaj   +1 more source

m6A modification in gastric cancer: the function of the YTH family of proteins [PDF]

, 2022
Maria Beatriz Alves Da Fonseca Samor De Almeida
core  

YTHDF1 regulates immune cell infiltration in gastric cancer via interaction with p53

Experimental and Therapeutic Medicine
The N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 1 (YTHDF1) has been assessed in several tumor types and holds significance in the tumor microenvironment (TME). Furthermore, p53, an important tumor suppressor, is closely associated with the TME.
Liao, Quan, Xiong, Jianping
openaire   +2 more sources

Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation

Gut, 2023
Ane Olazagoitia-Garmendia, Henar Rojas-Márquez, Maria del Mar Romero, Pamela Ruiz, Aloña Agirre-Lizaso, Yantao Chen, Maria Jesus Perugorria, Laura Herrero, Dolors Serra, Cheng Luo, Luis Bujanda, Chuan He, Ainara Castellanos-Rubio   +12 more
openaire   +2 more sources

The METTL3/m6A Reader Protein YTHDF1 Regulates Endothelial Cell Pyroptosis by Enhancing NLRP3 Expression to Affect Soft Tissue Injury

Journal of Inflammation Research
Xuesong Xie,1 Fang Fang2 1Department of Orthopedics, Xiangtan Central Hospital, Xiangtan, 411100, People’s Republic of China; 2Department of Anorectal, Xiangtan Central Hospital, Xiangtan, 411100, People’s Republic of ChinaCorrespondence: Fang Fang ...
Xie X, Fang F
doaj  

ADAMDEC1-driven CCL2-CCR2-PD-1 axis in esophageal squamous cell carcinoma: a dual threat of O-GlcNAcylation and m⁶A methylation in neoadjuvant therapy resistance and immune evasion. [PDF]

Cell Oncol (Dordr)
Cheng J, Ma H, Qian X, Xing W.
europepmc   +1 more source

RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review). [PDF]

Int J Mol Med
Liu S, Ma Z, Ji B, Zhu J, Yao S, Terai S, Tuo B, Li T, Liu X.   +8 more
europepmc   +1 more source

Integrated genetic analysis reveals synaptic m⁶A enrichment in high-risk autism genes. [PDF]

Front Mol Neurosci
Doijad S, Sakthivel D, Gowda NKC.
europepmc   +1 more source

m⁶A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development. [PDF]

EMBO J
Su R, Gao D, Du Z, Meng TG, Li C, Chen LN, Lin X, Cao C, Fan LH, Dong Y, Li S, Luo SM, Jiang S, Guo Z, Tian Y, Sun QY, Ou XH.   +16 more
europepmc   +1 more source