Results 141 to 150 of about 7,941 (215)

The role of RNA-modifying proteins in renal cell carcinoma [PDF]

Gene expression is one of the most critical cellular processes. It is controlled by complex mechanisms at the genomic, epigenomic, transcriptomic, and proteomic levels. Any aberration in these mechanisms can lead to dysregulated gene expression.
Alhammadi, Muna A, Bajbouj, Khuloud, Hamoudi, Rifat, Talaat, Iman M   +3 more
core  

YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges

Abstract Animals adapt to environmental challenges with long-term changes at the behavioral, circuit, cellular, and synaptic levels which often require new protein synthesis. The discovery of reversible N6-methyladenosine (m 6 A) modifications of mRNA has revealed an important layer
Zhuoyue Shi, Kailong Wen, Zhongyu Zou, Wenqin Fu, Kathryn Guo, Nabilah H Sammudin, Xiangbin Ruan, Shivang Sullere, Shuai Wang, Xiaochang Zhang, Gopal Thinakaran, Chuan He, Xiaoxi Zhuang   +12 more
openaire   +2 more sources

m⁶A-Modified hsa_circ_0002694 facilitates OSCC progression via the METTL14/YTHDC1/miR-616-3p/c-Myc axis. [PDF]

Head Face Med
Liu L, Xu B, Leng X, Li Y, Zhao J, Wu J, Deng J, Ma W.   +7 more
europepmc   +1 more source

YTHDF1 transcriptionally activated by TCF4 suppresses osteoblast ferroptosis in titanium nanoparticle-induced osteolysis by accelerating GPX4 and SLC7A11 translation. [PDF]

J Nanobiotechnology
Zhong D, Xie W, Liao Z, Liu H, Zhu L, Gao F, Li X, Yin Z, Xu G, Chen P, Tian J, Wang L, Yin K, Chen K, Wang C.   +14 more
europepmc   +1 more source

Magnesium ions facilitate osteogenic differentiation and intervertebral fusion <i>via</i> m6A methylation of RhoA mRNA. [PDF]

J Orthop Translat
Xu H, Li L, Zhang F, Shao M, Li C, Xue Y, Li D, Lin Z, Gong Z, Wu J, Luo Z, Shi Z, Xia X, Wang H, Ma X, Jiang J, Gu X, Liu Y, Lu X, Lyu F.   +19 more
europepmc   +1 more source

Epstein-Barr Virus Promotes Gastric Cancer Progression by Modulating m6A-Dependent YTHDF1-TSC22D1 Axis. [PDF]

Microorganisms
An YR, Jung J, Kwon KM, Kim JY, Lee MH, Lee JY, Lee M, Lee SK.   +7 more
europepmc   +1 more source

RNA m⁶A modification is a driver and therapeutic target in gastric cancer. [PDF]

Cell Biol Toxicol
Chen Q, Lu H, Li D, Liu T.
europepmc   +1 more source

YTHDF1 Control of Dendritic Cell Cross-Priming as a Possible Target of Cancer Immunotherapy [PDF]

Biochemistry, 2019
Daniel J. Kim, Akiko Iwasaki
openaire   +2 more sources

RNA N⁶-methyladenosine reader protein YTHDF1 promotes plasma cell differentiation via IRF4 regulation in systemic lupus erythematosus. [PDF]

Exp Mol Med
Lu S, Wei X, Zhu H, Li L, Zhang W, Du P, Yu Y, Zheng M, Hu Z, Jia S, Lu Q, Zhao M.   +11 more
europepmc   +1 more source

USP7 Drives Atherosclerosis by Promoting Ferroptosis in Vascular Endothelial Cells via the KIAA1429/NEAT1/CTCF Axis. [PDF]

Biol Proced Online
Dong B, Kou L, Yang JY, Li Y, Yang N.
europepmc   +1 more source