Sodium-myoinositol cotransporter-1 downstream of m6A methyltransferase WTAP exerts a potential carcinogenicity in diffuse large B-cell lymphoma progression. [PDF]
Li X, He X, Sun Y, Yang W.
europepmc +1 more source
The Regulatory Role of m6A Modification in the Function and Signaling Pathways of Animal Stem Cells. [PDF]
Yang X +5 more
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Pseudorabies virus infection reshapes the host epitranscriptome by globally suppressing but selectively elevating specific RNA modifications. [PDF]
Wang Y +6 more
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m6A regulators-based gene expression pattern is associated with immune microenvironment characteristics in hepatocellular carcinoma. [PDF]
Wang W +9 more
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RNA modifications: roles in immune cell biology and tumor regulation. [PDF]
Liu H +6 more
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Manipulation therapy alleviates neuropathic pain <i>via</i> the SOCS1 m<sup>6</sup>A epigenetic loop. [PDF]
Wu L +8 more
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Exploring the potential of <i>Schmidtea mediterranea</i> as a model for reproductive toxicity through analysis of sterility caused defective m<sup>6</sup>A RNA regulation. [PDF]
Tasaki J, Liu S, Rouhana L.
europepmc +1 more source
Epigenetic regulatory mechanisms and translational applications in idiopathic pulmonary fibrosis. [PDF]
Jiang M, Wang Q, Lyu Y, Hou X, Zhou X.
europepmc +1 more source
FMRP phosphorylation modulates neuronal translation through YTHDF1
RNA-binding proteins (RBPs) control messenger RNA fate in neurons. Here, we report a mechanism that the stimuli-induced neuronal translation is mediated by phosphorylation of a YTHDF1-binding protein FMRP. Mechanistically, YTHDF1 can condense with ribosomal proteins to promote the translation of its mRNA targets.
Zhongyu Zou, Jiangbo Wei, Yunhee Kang
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YTHDF1 Regulates Pulmonary Hypertension through Translational Control of MAGED1
American Journal of Respiratory and Critical Care Medicine, 2021Abstract Rationale Posttranscriptional modifications are implicated in vascular remodeling of pulmonary hypertension (PH). m6A (N6–methyladenosine) is an abundant RNA modification that is involved in various biological processes.
Li, Hu +13 more
openaire +2 more sources

