Degradation of zearalenone by microorganisms and enzymes [PDF]
PeerJ, 2023 Mycotoxins are toxic metabolites produced by fungi that may cause serious health problems in humans and animals. Zearalenone is a secondary metabolite produced by fungi of the genus Fusarium, widely exists in animal feed and human food.
Jiregna Gari, Rahma Abdella
doaj +5 more sources
Zearalenone and the Immune Response [PDF]
Toxins, 2021 Zearalenone (ZEA) is an estrogenic fusariotoxin, being classified as a phytoestrogen, or as a mycoestrogen. ZEA and its metabolites are able to bind to estrogen receptors, 17β-estradiol specific receptors, leading to reproductive disorders which include low fertility, abnormal fetal development, reduced litter size and modification at the level of ...
Cristina Valeria Bulgaru +3 more
openaire +4 more sources
Research Progress of Safety of Zearalenone: A Review
Toxins, 2022 Zearalenone, a mycotoxin produced by fungi of the genus Fusarium, widely exists in animal feed and human food. The structure of zearalenone is similar to estrogen, so it mainly has estrogenic effects on various organisms.
Xiao Han +6 more
doaj +2 more sources
Zearalenone disturbs the reproductive-immune axis in pigs: the role of gut microbial metabolites
Microbiome, 2022 Highlights I. Zearalenone directly and/or indirectly disturbs immune defense in the reproductive-immune axis; II. Zearalenone-induced toxicity on the reproductive-immune axis is accompanied by systemic inflammation caused by altered gut microbial ...
Shujin Wang +10 more
doaj +2 more sources
Toxins, 2022 Mitochondria hold redox homeostasis and energy metabolism as a crucial factor during oocyte maturation, while the exposure of estrogenic mycotoxin zearalenone causes developmental incapacity in porcine oocyte.
Jiehuan Xu +7 more
doaj +2 more sources
Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme [PDF]
Toxins, 2021 The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feed and is well known for its estrogenic effects in animals. Cattle are considered less sensitive to ZEN than pigs. However, ZEN has previously been shown to be converted to the highly estrogenic metabolite α-zearalenol (α-ZEL) in rumen fluid in vitro.
Christiane Gruber-Dorninger +9 more
openaire +5 more sources
Zearalenone intoxication of pigs [PDF]
Australian Veterinary Journal, 1984 SUMMARYMycotoxicosis due to ingestion of zearalenone was detected on 2 pig farms on the Atherton Tableland in northern Queensland. In one herd of 200 pigs, this resulted from feeding maize which had been stored with a high moisture content. In the other herd of 1400 pigs, it resulted from feeding sorghum grain which was rain affected before harvest ...
B. J. Blaney +2 more
openalex +5 more sources
The influence of mineral adsorbent „Minazel” on the reduction of residual zearalenone and its metabolites in cow's milk [PDF]
Veterinarski Glasnik, 2003 The results of the use of mineral adsorbent - Minazel, a preparation based on natural zeolite, in the prevention of mycotoxicoses and avoidance of zearalenone and its metabolites transfer into cow's milk were described in this paper.
Nešić Srđan +4 more
doaj +3 more sources
Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo [PDF]
Toxins, 2019 Zearalenone (ZEN)-degrading enzymes are a promising strategy to counteract the negative effects of this mycotoxin in livestock. The reaction products of such enzymes need to be thoroughly characterized before technological application as a feed additive can be envisaged.
Sebastian Fruhauf +11 more
openaire +5 more sources
Zearalenone and Its Metabolites—General Overview, Occurrence, and Toxicity
Toxins, 2021 Mycotoxins are secondary metabolites of filamentous fungi and represent one of the most common groups of food contaminants with low molecular weight.
Karolina Ropejko, M. Twarużek
semanticscholar +1 more source