Results 91 to 100 of about 4,964 (191)

CACLENS: A Multitask Deep Learning System for Enzyme Discovery

Advanced Science, Volume 13, Issue 9, 13 February 2026.
CACLENS, a multimodal and multi‐task deep learning framework integrating cross‐attention, contrastive learning, and customized gate control, enables reaction type classification, EC number prediction, and reaction feasibility assessment. CACLENS accelerates functional enzyme discovery and identifies efficient Zearalenone (ZEN)‐degrading enzymes.
Xilong Yi, Yingzhu Tan, Huikang Lin, Guoqing Zhang, Ye Tian, Aibo Wu   +5 more
wiley   +1 more source

Early-life exposure to mycotoxin zearalenone exacerbates aberrant immune response, oxidative stress, and mortality of Caenorhabditis elegans under pathogen Bacillus thuringiensis infection

Ecotoxicology and Environmental Safety
Zearalenone (ZEN) is a prevalent mycotoxin that severely impacts human and animal health. However, the possible interactions between ZEN exposure, pathogen infection, immune system, and reactive oxygen species (ROS) were rarely investigated.
Chun Ming How, Yong-Shan Li, Wei-Yun Huang, Chia-Cheng Wei   +3 more
doaj   +1 more source

Development of an UPLC-MS/MS method for the analysis of mycotoxins in rumen fluid with and without maize silage emphasizes the importance of using matrix-matched calibration [PDF]

, 2019
Ruminants are less susceptible to the effects of mycotoxins than monogastric animals as their rumen microbiota are claimed to degrade and/or deactivate at least some of these toxic compounds. However, the mycotoxin degradation is not well-known yet.
Croubels, Siska, De Baere, Siegrid, Debevere, Sandra, Fievez, Veerle, Haesaert, Geert, Rychlik, Michael   +5 more
core   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Advice on animal and public health risks of insects reared on former foodstuffs as raw material for animal feed

Food Risk Assess Europe, Volume 4, Issue 1, January 2026.
Abstract In the coming decades, there is expected to be a sharply increased demand for dietary proteins for humans and animals. As a result, there is an increasing focus on reared insects as a new source of protein. According to the Ministry of Agriculture, Nature and Food Quality (LNV), the use of food chain residual flows such as former foodstuffs as
L.F.F. Kox, D.T.H.M. Sijm
wiley   +1 more source

In Vitro Biotransformation of Zearalenone by Bacillus subtilis Strain 23830

Shipin gongye ke-ji
This study aimed to explore the potential application of probiotics for the safe removal of zearalenone (ZEN) from feed by screening and validating the ZEN transformation capability of a soil-derived Bacillus subtilis strain 23830.
Mengying WU, Yongli YE, Yang YANG, Jian JI, Wei WANG, Jijuan CAO, Xiulan SUN   +6 more
doaj   +1 more source

Use of Cold Plasma for Phytosanitation and Decontamination of Food Products: A Review

Future Postharvest and Food, Volume 2, Issue 4, Page 390-410, December 2025.
Applications of cold plasma in food industry. ABSTRACT Consumers are increasingly demanding healthy and nutrient‐rich food. Although conventional thermal processing techniques (pasteurization, sterilization, and blanching) ensure food safety and extend shelf life, they often negatively impact nutritional value and sensory quality, and they also consume
Chandel Anu, Janifer Raj Xavier, Chauhan Om Prakash   +2 more
wiley   +1 more source

Vigor King mitigates spermatogenic disorders caused by environmental estrogen zearalenone exposure

Ecotoxicology and Environmental Safety
Zearalenone (ZEN) has been shown to cause reproductive damage by inducing oxidative stress. Astaxanthin and L-carnitine are widely used to alleviate oxidative stress and promote sperm maturation.
Ning Zuo, Rui Ting Wang, Wen Meng Bian, Xuan Liu, Bao Quan Han, Jun Jie Wang, Wei Shen, Lan Li   +7 more
doaj   +1 more source

The impact of deoxynivalenol on pigeon health : occurrence in feed, toxicokinetics and interaction with salmonellosis [PDF]

, 2016
Seed-based pigeon diets could be expected to result in exposure of pigeons to mycotoxins such as deoxynivalenol (DON). Ingestion of low to moderate contamination levels of DON may impair intestinal health, immune function and/or pathogen fitness ...
Antonissen, Gunther, Audenaert, Kris, Broekaert, Nathan, Croubels, Siska, De Saeger, Sarah, Devreese, Mathias, Ducatelle, Richard, Haesebrouck, Freddy, Haesendonck, Roel, Martel, An, Pasmans, Frank, Verbrugghe, Elin   +11 more
core   +4 more sources