Zirconium-89 - Open Access .click

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Production of no-carrier-added zirconium-89 for positron emission tomography

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1991
The production and radiochemical separation of 89Zr from deuteron irradiation of natural yttrium targets is described. The production is optimized in order to minimize the level of the long lived 88Zr. The yield of 89Zr at 16 MeV incident deuteron energy is 18 ± 1.5 GBq/C (1.8 ± 0.15 mCi/μ Ah) for a target thickness of 240 mg/cm2 and the contamination ...
Zweit, J., Downey, S., Sharma, H. L.
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Hydroxamate column-based purification of zirconium-89 (89Zr) using an automated fluidic platform

Applied Radiation and Isotopes, 2018
Zirconium-89 (89Zr) is a long-lived (t1/2 = 78.4h) positron-emitting isotope that is useful for positron emission tomography (PET) based diagnostic imaging using radiolabeled antibodies. Hydroxamate resin columns are predominantly used for the purification of 89Zr from cyclotron bombarded natY targets dissolved in strong HCl.
Matthew J, O'Hara +4 more
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Quantitative imaging characteristics of zirconium-89 on Gemini Time-Of-Flight PET/CT

Nuclear Medicine Communications, 2016
Interest in PET imaging using zirconium-89 (Zr) (t1/2=78.41 h)-labeled tracers for the tracking and quantification of monoclonal antibodies (mAbs) is growing, mainly because of its well-matched physical half-life with the biological half-life of intact mAbs.
Sitah F, Alanazi +5 more
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Production of radioimmunoPET grade zirconium-89

2023
MohammadpourGhazi, Fatemeh +6 more
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Fully automated zirconium-89 antibody labeling and purification