Results 51 to 60 of about 29,405 (257)

Inhibitory Effects of Edaravone, a Free Radical Scavenger, on Cytokine-induced Hyperpermeability of Human Pulmonary Microvascular Endothelial Cells:A Comparison with Dexamethasone and Nitric Oxide Synthase Inhibitor [PDF]

, 2015
Lung hyperpermeability affects the development of acute respiratory distress syndrome (ARDS), but therapeutic strategies for the control of microvascular permeability have not been established.
Fujii, Yousuke, Morishima, Tsuneo, Nosaka, Nobuyuki, Saito, Yukie, Tsuge, Mitsuru, Tsukahara, Hirokazu, Yamada, Mutsuko, Yamashita, Nobuko, Yashiro, Masato   +8 more
core   +1 more source

En face optical coherence tomography of foveal microstructure in full-thickness macular hole: a model to study perifoveal müller cells. [PDF]

, 2015
PURPOSE: To characterize perifoveal intraretinal cavities observed around full-thickness macular holes (MH) using en face optical coherence tomography and to establish correlations with histology of human and primate maculae.
Behar-Cohen, F., Bergin, C., Crisanti, P., Lumbroso, B., Matet, A., Moulin, A., Rispoli, M., Savastano, M.C.   +7 more
core   +1 more source

Neuronal connexin36 association with zonula occludens‐1 protein (ZO‐1) in mouse brain and interaction with the first PDZ domain of ZO‐1 [PDF]

European Journal of Neuroscience, 2004
AbstractAmong the 20 members in the connexin family of gap junction proteins, only connexin36 (Cx36) is firmly established to be expressed in neurons and to form electrical synapses at widely distributed interneuronal gap junctions in mammalian brain.
Xinbo, Li, Carl, Olson, Shijun, Lu, Naomi, Kamasawa, Thomas, Yasumura, John E, Rash, James I, Nagy   +6 more
openaire   +2 more sources

Archidendron clypearia extract: Modulating intestinal inflammation and enhancing disease resistance in aquacultured American bullfrogs (Aquarana catesbeiana)

Aquaculture Reports
Intestinal inflammation and bacterial infections challenges in the aquaculture of American bullfrogs (Aquarana catesbeiana), impacting their health and productivity.
Kesong Chen, Han Lin, Jingyang Sun, Hua Li, Jie Ma, Zhendong Qin, Biao Jiang, Wei Li, Qing Wang, Youlu Su, Li Lin, Chun Liu   +11 more
doaj   +1 more source

Longitudinal Changes to Tight Junction Expression and Endothelial Cell Integrity in a Mouse Model of Sterile Corneal Inflammation [PDF]

, 2016
PURPOSE: We previously reported that applying toll-like receptor (TLR) ligands to an injured cornea induces corneal edema at 24 hours, which subsides by 1 week.
Larkin, DFP
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Enteropathogenic Escherichia coli , Shigella flexneri , and Listeria monocytogenes Recruit a Junctional Protein, Zonula Occludens-1, to Actin Tails and Pedestals [PDF]

Infection and Immunity, 2007
ABSTRACT Enteropathogenic Escherichia coli , Shigella flexneri , and Listeria monocytogenes induce localized actin polymerization at the cytoplasmic face of the plasma membrane or within the host cytoplasm, creating unique actin-rich structures termed ...
Miyuki, Hanajima-Ozawa, Takeshi, Matsuzawa, Aya, Fukui, Shigeki, Kamitani, Hiroe, Ohnishi, Akio, Abe, Yasuhiko, Horiguchi, Masami, Miyake   +7 more
openaire   +2 more sources

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

Advanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin, Sayba Z. Chowdhury, Maurice de Wit, Rania Head, Kiki Bals, Erwin Brosens, Marvin M. van Luijn, Hayri E. Balcioglu, Angelo Accardo, Pim J. French   +9 more
wiley   +1 more source

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

AIDS Research and Therapy, 2009
Background HIV-infected individuals are at increased risk for acute and chronic airway disease even though there is no evidence that the virus can infect the lung epithelium.
Jacob Barbara A, Joshi Pratibha C, Fan Xian, Lassiter Coy, Sutliff Roy L, Jones Dean P, Koval Michael, Guidot David M   +7 more
doaj   +1 more source

The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. [PDF]

Proceedings of the National Academy of Sciences, 1996
The junction-associated protein zonula occludens-1 (ZO-1) is a member of a family of membrane-associated guanylate kinase homologues thought to be important in signal transduction at sites of cell-cell contact. We present evidence that under certain conditions of cell growth, ZO-1 can be detected in the nucleus.
C J, Gottardi, M, Arpin, A S, Fanning, D, Louvard   +3 more
openaire   +2 more sources