Ankrd1-mediated signaling is supported by its interaction with zonula occludens-1 [PDF]
The muscle ankyrin repeat protein Ankrd1 is localized in a mechanosensory complex of the sarcomeric I-band. It is involved in signaling pathways activated in response to mechanical stretch.
Nestorović Aleksandra +4 more
doaj +3 more sources
Lens connexins α3Cx46 and α8Cx50 interact with zonula occludens protein-1 (ZO-1) [PDF]
Connexin α1Cx43 has previously been shown to bind to the PDZ domain–containing protein ZO-1. The similarity of the carboxyl termini of this connexin and the lens fiber connexins α3Cx46 and α8Cx50 suggested that these connexins may also interact with ZO-1.
Baruch, Amos +6 more
core +7 more sources
Spatial Overlap of Claudin- and Phosphatidylinositol Phosphate-Binding Sites on the First PDZ Domain of Zonula Occludens 1 Studied by NMR [PDF]
Background: The tight junction is an intercellular adhesion complex composed of claudins (CLDs), occludin, and the scaffolding proteins zonula occludens 1 (ZO-1) and its two paralogs ZO-2 and ZO-3.
Hidekazu Hiroaki +7 more
doaj +2 more sources
Neuroprotective effects of ulinastatin on Escherichia coli meningitis rats through inhibiting PKCα phosphorylation and reducing zonula occludens-1 degradation [PDF]
Ulinastatin, a broad-spectrum inflammatory inhibitor widely employed in the management of severe pancreatitis and sepsis, has not been extensively investigated for its therapeutic potential in bacterial meningitis.
Xiaolan Zheng +9 more
doaj +2 more sources
Expression of Zonula Occludens-1 and Claudin-1 Proteins in Japanese Quails Testis
İlknur ÜNDAĞ +1 more
doaj +2 more sources
Immunohistochemical Analysis of Vimentin and Zonula Occludens-1 in Placentas of Patients with PPROM
Background: We aimed to investigate the immunohistochemical staining of vimentin and zonula occludens-1 (ZO-1) expression in the placentas of pregnant women with preterm premature rupture of membranes (PPROM).
Fuat Zaman +5 more
doaj +3 more sources
Loss of Zonula Occludens-1 (ZO-1) Enhances Angiogenic Signaling in Ovarian Cancer Cells. [PDF]
Zonula occludens-1 (ZO-1), encoded by the TJP1 gene, is a crucial scaffolding protein within tight junctions that maintains epithelial and endothelial barrier integrity. In addition to its structural role, ZO-1 participates in signal transduction pathways that influence various cellular processes such as proliferation, differentiation, and apoptosis ...
Choi S +9 more
europepmc +3 more sources
Zonula occludens-1 distribution and barrier functions are affected by epithelial proliferation and turnover rates. [PDF]
AbstractZonula occludens‐1 (ZO‐1) is a scaffolding protein of tight junctions, which seal adjacent epithelial cells, that is also expressed in adherens junctions. The distribution pattern of ZO‐1 differs among stratified squamous epithelia, including that between skin and oral buccal mucosa.
Imafuku K +8 more
europepmc +3 more sources
Hypertonic Stress Promotes the Upregulation and Phosphorylation of Zonula Occludens 1 [PDF]
Tight junction molecules form a barrier between adjacent cells and mediate the cells’ ability to develop membranes that constitute boundaries of different compartments within the body. Membranes with selective ion and water passage are important for the electrolyte and water homeostasis in the kidney.
Cornelia, Then +5 more
openaire +4 more sources
IntroductionFermented egg-milk peptides (FEMPs) could enhance the colon-intestinal barrier and upgrade the expression of zonula occludens-1 and mucin 2.
Siwen Lyu +9 more
doaj +1 more source

