Results 31 to 40 of about 31,457 (207)
Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]
, 2017 Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo +13 more
core +2 more sources
Expression of Tight Junction Proteins Is Altered in Bladder Cancer
Analytical Cellular Pathology, 2020 Bladder cancer (BC) is one of the tumors which occur most frequently in urological system, but less is known about the expression of tight junction proteins and its clinical significance in BC.
Bangbin Chen, Renge Bu, Xuewen Xu
doaj +1 more source
Aquaculture Reports, 2023 s: This trial was performed to investigate the effects of Clostridium butyricum on growth and intestinal health of hybrid groupers (Epinephelus lanceolatus♂ × E. fuscoguttatus♀). 300 hybrid groupers were fed five diets containing C.
Keng Yang +7 more
doaj +1 more source
Zonula occludens 1 as a novel biomarker in decompensated alcoholic cirrhosis with hepatorenal syndrome [PDF]
Exploration of Digestive DiseasesAim: Our previous study provided evidence that systemic zonula occludens (ZO) 1 levels are elevated in cirrhotic and hepatocellular carcinoma (HCC) patients. Here, we aimed to evaluate serum ZO-1 levels in patients with decompensated alcoholic cirrhosis (
Balasubramaniyan Vairappan +2 more
doaj +1 more source
Effects of acute and chronic disease on cell junctions in mouse liver
EXCLI Journal : Experimental and Clinical Sciences, 2023 Cell junctions, including anchoring, occluding and communicating junctions, play an indispensable role in tissue architecture and homeostasis. Consequently, malfunctioning of cell junctions is linked with a wide range of disorders, including in liver ...
Raf Van Campenhout +2 more
doaj +1 more source
The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription [PDF]
, 2009 Epithelial tight junctions recruit different types of signalling proteins that regulate cell proliferation and differentiation. Little is known about how such proteins interact functionally and biochemically with each other.
Aijaz, S. +4 more
core +2 more sources
Telmisartan Increases the Permeability of Endothelial Cells through Zonula Occludens-1
Biological and Pharmaceutical Bulletin, 2009 Angiotensin receptor-1 blockers (ARBs) have been used for the treatment of atherosclerosis. Tight junctions are very important in the regulation of cellular permeability which may have a profound role in atherosclerosis. The relationship between them is unresolved.
Chang, Bian, Yihua, Wu, Peng, Chen
openaire +3 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background α Carboxyl terminus 1 (αCT1) is a 25–amino acid therapeutic peptide incorporating the zonula occludens‐1 (ZO‐1)–binding domain of connexin 43 (Cx43) that is currently in phase 3 clinical testing on chronic wounds.
Jingbo Jiang +12 more
doaj +1 more source
Antioxidants, 2021 Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process.
Adriana Cortés +8 more
doaj +1 more source
Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]
, 2016 Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core +1 more source