Results 41 to 50 of about 31,457 (207)

En face optical coherence tomography of foveal microstructure in full-thickness macular hole: a model to study perifoveal müller cells. [PDF]

, 2015
PURPOSE: To characterize perifoveal intraretinal cavities observed around full-thickness macular holes (MH) using en face optical coherence tomography and to establish correlations with histology of human and primate maculae.
Behar-Cohen, F., Bergin, C., Crisanti, P., Lumbroso, B., Matet, A., Moulin, A., Rispoli, M., Savastano, M.C.   +7 more
core   +1 more source

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption [PDF]

, 2020
The epithelial sodium channel (ENaC) can increase the colonic absorptive capacity for salt and water. Campylobacter concisus is a common pathogenic epsilonproteobacterium, causing enteritis and diarrhea. It can induce barrier dysfunction in the intestine,
Bereswill, Stefan, Butkevych, Eduard, Bücker, Roland, Fromm, Anja, Genger, Claudia, Heimesaat, Markus M., Kløve, Sigri, Lee, In-Fah Maria, Lobo de Sá, Fábia Daniela, Mousavi, Soraya, Nagel, Oliver, Nattramilarasu, Praveen Kumar, Nielsen, Hans Linde, Schulzke, Jörg-Dieter, Schweiger, Michal R., Troeger, Hanno   +15 more
core   +2 more sources

Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni [PDF]

, 2019
Campylobacter jejuni (C. jejuni) is the most common cause of foodborne gastroenteritis worldwide. The bacteria induce diarrhea and inflammation by invading the intestinal epithelium. Curcumin is a natural polyphenol from turmeric rhizome of Curcuma longa,
Bereswill, Stefan, Butkevych, Eduard, Bücker, Roland, Fromm, Anja, Golz, Julia C., Heimesaat, Markus M., Kehrenberg, Corinna, Kittler, Sophie, Lobo de Sá, Fábia Daniela, Moos, Verena, Mousavi, Soraya, Nattramilarasu, Praveen Kumar, Schulzke, Jörg-Dieter, Seinige, Diana, Stingl, Kerstin   +14 more
core   +1 more source

Zonula occludens‐1 and connexin 43 expression in the failing human heart [PDF]

Journal of Cellular and Molecular Medicine, 2007
AbstractFocal disorganization of gap junctional distribution and down‐regulation of the major gap junctional protein connexin 43 are typical features of myocardial remodelling in the failing human heart. Increasing evidence indicates that connexin 43 interacts with zonula‐occludens‐1 (ZO‐1), and it has recently been shown that ZO‐1 promotes the ...
openaire   +2 more sources

Cx43 and the Actin Cytoskeleton: Novel Roles and Implications for Cell-Cell Junction-Based Barrier Function Regulation

Biomolecules, 2020
Barrier function is a vital homeostatic mechanism employed by epithelial and endothelial tissue. Diseases across a wide range of tissue types involve dynamic changes in transcellular junctional complexes and the actin cytoskeleton in the regulation of ...
Randy E. Strauss, Robert G. Gourdie
doaj   +1 more source

Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. [PDF]

, 2020
Background & aimsBiotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis.
Cahalan, Michael D, Hwang, Michael, Nakasaki, Manando, Sabui, Subrata, Said, Hamid M, Skupsky, Jonathan   +5 more
core  

Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin [PDF]

, 2006
Epithelial tight junctions participate in the regulation of gene expression by controlling the activity of transcription factors that can interact with junctional components.
Balda, MS, Buchert, M, Choquet, A, Hollande, F, Kavanagh, E, Matter, K, Tsapara, A   +6 more
core   +1 more source

Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin [PDF]

, 2020
Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not well understood.
Baltazar, Murielle, Bricio-Moreno, Laura, Dowson, Christopher G., Everett, Dean B., Jacques, Laura C., Kadioglu, Aras, Khandaker, Shadia, Neill, Daniel R., Panagiotou, Stavros, Senghore, Madikay, Xu, Rong, Yang, Marie   +11 more
core   +4 more sources

Connexins: synthesis, post-translational modifications, and trafficking in health and disease [PDF]

, 2018
Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate direct intercellular communication, a critical feature for the development, function, and homeostasis of tissues and organs.
Aasen, Trond, Johnstone, Scott, Koval, Michael, Lynn, K. Sabrina, Universitat Autònoma de Barcelona, Vidal-Brime, Laia   +5 more
core   +3 more sources

Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome

Journal of the Formosan Medical Association, 2014
Unique barrier properties of the urothelial surface membrane permit urine storage without contents leak into the bloodstream. Previous reports suggested that the bladder urothelial barrier might be compromised in interstitial cystitis/painful bladder ...
Jane-Dar Lee, Ming-Huei Lee
doaj   +1 more source