Results 101 to 110 of about 26,894 (230)

Sulfur mustard-stimulated proteases and their inhibitors in a cultured normal human epidermal keratinocytes model: A potential approach for anti-vesicant drug development

open access: yesToxicology Reports, 2016
Protease stimulation in cultured normal human epidermal keratinocytes (NHEK) due to sulfur mustard (SM) exposure is well documented. However, the specific protease(s) stimulated by SM and the protease substrates remain to be determined. In this study, we
Xiannu Jin, Radharaman Ray, Prabhati Ray
doaj   +1 more source

Matrix Metalloproteinases and Glaucoma Treatment. [PDF]

open access: yes, 2020
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed   +3 more
core  

Deteksi Aktivitas Fibrinolitik Isolat Bakteri WU 021055* Asal Perairan Pantai Papuma Jember Menggunakan Zimografi

open access: yesGlobal Medical & Health Communication, 2017
Abstrak Bakteri merupakan sumber penting berbagai enzim termasuk enzim fibrinolitik. Enzim ini diperlukan untuk mendegradasi bekuan darah pada orang yang mengalami penyakit trombosis.
Evi Umayah Ulfa   +4 more
doaj  

A FAST AND SENSITIVE ZYMOGRAPHY METHOD OF PEROXIDASE ACTIVITY DETERMINATION USING SODIUM ACETATE BUFFER

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2019
By changing the buffer composition from phosphate to acetate (in both cases, the pH value was 6.0), the sensitivity of the estimation of peroxidase activity in polyacrylamide gels was improved from 4 µg/well to 0.4 µg/well.
Gheorghița MENGHIU   +2 more
doaj   +1 more source

Assessment and partial purification of serine protease inhibitors from Rhipicephalus (Boophilus) annulatuslarvae

open access: yesRevista Brasileira de Parasitologia Veterinária
Ticks are rich sources of serine protease inhibitors, particularly those that prevent blood clotting and inflammatory responses during blood feeding. The tick Rhipicephalus (Boophlus) annulatusis an important ectoparasite of cattle.
Sedigheh Nabian   +5 more
doaj   +1 more source

Peritumoral administration of GPI-anchored TIMP-1 inhibits colon carcinoma growth in Rag-2 gamma chain-deficient mice [PDF]

open access: yes, 2009
Exogenous application of recombinant TIMP-1 protein modified by addition of a glycosylphosphatidylinositol (GPI) anchor allows efficient insertion of the fusion protein into cell membranes.
Djafarzadeh, Roghieh   +6 more
core   +1 more source

The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects [PDF]

open access: yes, 2017
Este es el manuscrito que fue aceptado y que finalmente se publicó en Cancer Letters con el DOI: 10.1016/j.canlet.2016.10.037The natural bioactive compound damnacanthal inhibits several tyrosine kinases.
García-Vilas, Javier A.   +4 more
core  

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure [PDF]

open access: yes, 2015
Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR).
Ampe, Christophe   +16 more
core   +3 more sources

Ex vivo Follicle Rupture and in situ Zymography in Drosophila

open access: yesBio-Protocol, 2018
Ovulation, the process of releasing a mature oocyte from the ovary, is crucial for animal reproduction. In order for the process of ovulation to occur, a follicle must be fully matured and signaled to rupture from the ovary.
Elizabeth Knapp   +2 more
doaj   +1 more source

Zymography of proteases in honey bees (Apis Mellifera) infected with Nosema ceranae [PDF]

open access: yesVeterinarski Glasnik
Nosemosis is one of the most important honey bee diseases and is caused by two fungal species of the genus Nosema, i.e., Nosema apis and Nosema ceranae.
Doghuzlu Mohammad Afrasiabi   +5 more
doaj   +1 more source

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