Results 91 to 100 of about 26,894 (230)
Three‐dimensional patient‐derived endometriosis model for drug evaluation
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 629-646, April 2026.In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Yuqi Li +10 more
wiley +1 more source
HGF modulates actin cytoskeleton remodeling and contraction in testicular myoid cells [PDF]
, 2015 The presence of the HGF/Met system in the testicular myoid cells was first discovered by our group. However, the physiological role of this pathway remains poorly understood. We previously reported that HGF increases uPA secretion and TGF-β activation in
Angela, Catizone +6 more
core +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.ABSTRACT Hypertensive heart disease is characterised by ventricular remodelling and interstitial fibrosis, in which dysregulation of the renin–angiotensin system (RAS) plays a pivotal role. This study investigated whether the transcription factor CCAAT/enhancer‐binding protein β (C/EBPβ) attenuates hypertensive myocardial fibrosis and remodelling by ...
Yuanyuan Tie +7 more
wiley +1 more source
Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]
, 2011 Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong +4 more
core +1 more source
Advanced Functional Materials, Volume 36, Issue 23, 19 March 2026.A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source
Matrix metalloproteinases 2 and 9 in rabbits with doxorubicin-induced cardiomyopathy
Pesquisa Veterinária Brasileira: Some studies have shown the role played by matrix metalloproteinases and their inhibitors in doxorubicin cardiotoxicity. In this study, we sought to investigate how plasma and myocardial MMP 2 and 9 perform in rabbits with doxorubicin-induced ...
Sheila S.S. Nogueira +7 more
doaj +1 more source
Endolysin Expression, Purification and Activity Determination by Zymography
Bio-Protocol, 2014 Endolysins are peptidoglycan-degrading (muralytic) enzymes produced by many bacteriophages for cell lysis of the host bacterium. The enzymatic activity of muralytic enzymes can be assayed qualitatively using a zymogram containing incorporated ...
Alexander Westbye +2 more
doaj +1 more source
Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells [PDF]
, 2017 Indexación: Web of Science; Scopus.Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer ...
Arias, J.I. +3 more
core +1 more source
The Journal of Pathology, Volume 268, Issue 3, Page 249-262, March 2026.Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou +3 more
wiley +1 more source
Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection [PDF]
, 2019 Pollens are well-known triggers of respiratory allergies and asthma. The pollen burden in today's ambient air is constantly increasing due to rising climate change and air pollution.
Gevaert, Kris +6 more
core +3 more sources