Results 11 to 20 of about 14,446 (183)
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2012 Angiostrongylus costaricensis is a nematode that causes abdominal angiostrongyliasis, a widespread human parasitism in Latin America. This study aimed to characterize the protease profiles of different developmental stages of this helminth.
Karina Mastropasqua Rebello +7 more
doaj +1 more source
Toxins, 2022 Viperidae snakes are the most important agents of snakebites in Brazil. The protein composition of snake venoms has been frequently analyzed by means of electrophoretic techniques, but the interaction of proteins in venoms has barely been addressed.
Natacha Ferreira de Oliveira +2 more
doaj +1 more source
Detection of proteolytic activity by covalent tethering of fluorogenic substrates in zymogram gels
BioTechniques, 2018 Current zymographic techniques detect only a subset of known proteases due to the limited number of native proteins that have been optimized for incorporation into polyacrylamide gels.
Ameya A Deshmukh +2 more
doaj +1 more source
Biomolecules, 2023 Background: The aim of the study was to longitudinally evaluate the association between MMP-2, MMP-9, TIMP-1 and chest radiological findings in COVID-19 patients.
Maria Antonella Zingaropoli +17 more
doaj +1 more source
Zymography of Metalloproteinases
Current Protocols in Protein Science, 2003 AbstractZymography is an electrophoretic technique enabling visualization of the number and approximate size of peptidases in a sample on the basis of their hydrolysis of a protein substrate within the gel. The technique is particularly useful for analyzing the peptidase composition of complex biological samples because visualization depends directly ...
Troeberg, L, Nagase, H
openaire +2 more sources
Indian Journal of Dental Research, 2016 Aim: The aim of this study was to comparatively assess the gelatinolytic activity of matrix metalloproteinases(MMPs) and Cysteine Cathepsins (CCs) in the adhesive interface using etch and rinse adhesive at different time intervals using zymographic ...
Sekar Mahalaxmi +3 more
doaj +1 more source
Toxins, 2017 Background: Medusozoans utilize explosively discharging penetrant nematocysts to inject venom into prey. These venoms are composed of highly complex proteins and peptides with extensive bioactivities, as observed in vitro.
Yang Yue +8 more
doaj +1 more source
Contrasting distribution of enzyme activities in the rhizosphere of European beech and Norway spruce
Frontiers in Plant Science, 2022 Recent policies and silvicultural management call for forest regeneration that involve the selection of tree species able to cope with low soil nutrient availability in forest ecosystems.
Bin Song +5 more
doaj +1 more source
Environmental Identification of Novel Enzymes for Polyurethane and Polyamide Degradation
Angewandte Chemie, EarlyView.Heteroatom‐containing plastics such as polyurethanes and nylons are produced at scale yet remain largely unrecycled. Biocatalysts offer a promising route to depolymerization under mild conditions. Here, we present a screening platform for the discovery of novel polyurethane‐ and nylon‐degrading enzymes from environmental samples and demonstrate ...
Malthe Kjær Bendtsen +17 more
wiley +2 more sources