Results 41 to 50 of about 26,894 (230)

Sphingosine 1-phosphate receptor 1 is required for MMP-2 function in bone marrow mesenchymal stromal cells: implications for cytoskeleton assembly and proliferation [PDF]

, 2018
Bone marrow-derived mesenchymal stromal cell- (BM-MSC-) based therapy is a promising option for regenerative medicine. An important role in the control of the processes influencing the BM-MSC therapeutic efficacy, namely, extracellular matrix remodelling
Anderloni, Giulia, Chellini, Flaminia, Frati, Alessia, Matteini, Francesca, Meacci, Elisabetta, Nosi, Daniele, Pierucci, Federica, Sassoli, Chiara, Tani, Alessia, Vestri, Ambra, Zecchi-Orlandini, Sandra   +10 more
core   +4 more sources

Escherichia coli induces apoptosis and proliferation of mammary cells [PDF]

, 2001
Mammary cell apoptosis and proliferation were assessed after injection of Escherichia coli into the left mammary quarters of six cows. Bacteriological analysis of foremilk samples revealed coliform infection in the injected quarters of four cows.
AD Metcalfe, AJ Bramley, AV Capuco, AV Capuco, AW Hill, AW Hill, B Zavizion, BR Rueda, C Kampf, C Legrand, CA Wesson, CB Thompson, CM Alexander, CR Roh, DA Siwik, DE Shuster, DE Shuster, GM Swank, GR Merlo, H Heermeier, JM Adams, JS Hogan, K Schorr, K Schorr, KB Reddy, KR Matthews, KW Bayles, LA Rudolph-Owen, LG Sheffield, LR Lund, M Colitti, M Li, M Li, ME Burow, MM Keane, N Boudjellab, N Boudreau, NA Thornberry, NR Keller, P Maloof, PA Furth, R Blowey, R Strange, RB Hazan, RJ Eberhart, RJ Eberhart, S Ohta, S Pullan, T Tanaka, UK Mebmer, VC Farr, X Li, YJ Tzeng   +52 more
core   +2 more sources

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis. [PDF]

, 2016
The invasion-promoting MT1-MMP is a cell surface-associated collagenase with a plethora of critical cellular functions. There is a consensus that MT1-MMP is a key protease in aberrant pericellular proteolysis in migrating cancer cells and, accordingly, a
Cieplak, Piotr, Ge, Xin, Nam, Dong Hyun, Remacle, Albert G, Shiryaev, Sergey A, Strongin, Alex Y   +5 more
core   +1 more source

Detection of Matrix Metalloproteinases by Zymography [PDF]

, 2017
Matrix metalloproteinases (MMPs) represent more than 20 zinc-containing endopeptidases that cleave internal peptide bonds, leading to protein degradation. They play a critical role in many physiological cell functions, including tissue remodeling, embryogenesis, and angiogenesis.
Rajeev B, Tajhya, Rutvik S, Patel, Christine, Beeton   +2 more
openaire   +2 more sources

In Drosophila Hemolymph, Serine Proteases Are the Major Gelatinases and Caseinases

Insects
After separation on gel zymography, Drosophila melanogaster hemolymph displays gelatinase and caseinase bands of varying sizes, ranging from over 140 to 25 kDa.
Jean-Luc Gatti, Séverine Lemauf, Maya Belghazi, Laury Arthaud, Marylène Poirié   +4 more
doaj   +1 more source

Zymography for Picogram Detection of Lipase and Esterase Activities

Molecules, 2021
Lipases and esterases are important catalysts with wide varieties of industrial applications. Although many methods have been established for detecting their activities, a simple and sensitive approach for picogram detection of lipolytic enzyme quantity ...
Andre Mong Jie Ng, Hongfang Zhang, Giang Kien Truc Nguyen   +2 more
doaj   +1 more source

Co-Emergence of Specialized Endothelial Cells from Embryonic Stem Cells. [PDF]

, 2018
A well-formed and robust vasculature is critical to the health of most organ systems in the body. However, the endothelial cells (ECs) forming the vasculature can exhibit a number of distinct functional subphenotypes like arterial or venous ECs, as well ...
Douglas, Simone A, Fan, Yuhong, Kumar, Ashwath, Lin, Zhiqiang, Madfis, Nicole, McCloskey, Kara E, Platt, Manu O   +6 more
core   +1 more source

Development of an improved Pseudoalteromonas haloplanktis TAC125 strain for recombinant protein secretion at low temperature [PDF]

, 2008
Background: In a previous paper, we reported the accomplishment of a cold gene-expression system for the recombinant secretion of heterologous proteins in Pseudoalteromonas haloplanktis TAC125.
CIRULLI C., DE VIZIO D., PARRILLI, ERMENEGILDA, TUTINO, MARIA LUISA   +3 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Promising perspectives for ruminal protection of polyunsaturated fatty acids through polyphenol-oxidase-mediated crosslinking of interfacial protein in emulsions

Animal, 2018
Previously, polyunsaturated fatty acids (PUFA) from linseed oil were effectively protected (>80%) against biohydrogenation through polyphenol-oxidase-mediated protein crosslinking of an emulsion, prepared with polyphenol oxidase (PPO) extract from potato
N. De Neve, B. Vlaeminck, F. Gadeyne, E. Claeys, P. Van der Meeren, V. Fievez   +5 more
doaj   +1 more source