Results 61 to 70 of about 21,615 (216)

Alcohol exposure promotes cell communication network 1 cleavage in esophageal adenocarcinoma cells exclusively

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
An illustration shows how cell communication network 1 (CCN1) is involved in the normal esophagus, esophageal squamous cell carcinoma (ESCC), and esophageal adenocarcinoma (EAC) after alcohol exposure. Alcohol exposure upregulates CCN1 expression in the esophageal epithelium, with or without esophageal cancer. In normal individuals, CCN1 repairs tissue
Wula Aladan   +6 more
wiley   +1 more source

Gelatin zymography of MMP-9 activity.

open access: yes, 2012
No difference in gelatinolytic activity is observed between PyMT, Lcn2+/+ and PyMT, Lcn2−/− mice, either in tumors or in plasma. A, zymography of tumors from PyMT, Lcn2+/+ (WT) and PyMT, Lcn2−/− (KO) mice with purified human MMP-9 (hMMP-9) as standard [2]
Eric Santoni-Rugiu (156947)   +9 more
core   +1 more source

Effect of corticosteroids and long-acting ß2- agonists in a human cell culture based "in vitro" model of airway inflammation and tissue remodeling [PDF]

open access: yes, 2006
Asthma and chronic obstructive pulmonary disease (COPD) are characterized by chronic airway inflammation and remodeling. In non-pathological conditions tissue homeostasis is maintained by the balance between extracellular matrix (ECM) synthesis and ...
Goulet, Stéphanie
core   +1 more source

Study of metalloproteinases in the blood of goats experimentally infected with caprine encephalitis arthritis virus

open access: yesSemina: Ciências Agrárias, 2020
Caprine arthritis encephalitis is a lentiviral disease that leads to considerable losses in goat farming. In the acute phase of viral infection, though antiviral antibodies are produced by the host’s immune system, they are not sufficient to be detected ...
Ylana Santos de Galiza   +6 more
doaj   +1 more source

Quantitation of the active alpha-2-macroglobulin by trypsin protease zymography [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
A simple and reliable method for the determination of the concentration and function of alpha-2-macroglobulin (α2M) by zymography was developed. The method is based on the covalent binding of α2M and trypsin followed by non-reducing PAGE and zymography ...
Gligorijević Nikola   +4 more
doaj   +1 more source

Upregulation of P2Y2R, Active uPA, and PAI-1 Are Essential Components of Hantavirus Cardiopulmonary Syndrome

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Sin Nombre virus (SNV) causes hantavirus cardiopulmonary pulmonary syndrome (HCPS) with the loss of pulmonary vascular endothelial integrity, and pulmonary edema without causing cytopathic effects on the vascular endothelium. HCPS is associated primarily
Virginie Bondu   +10 more
doaj   +1 more source

Therapeutic targeting of bleomycin‐induced pulmonary fibrosis by human bone marrow mesenchymal stem cell‐derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5423-5439, September 2026.
Abstract Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell‐derived extracellular vesicles (BM‐MSC‐EVs) with an IPF treatment, pirfenidone (PFD), in mature adult mice with established pulmonary ...
Jennie S. Charoenphannathon   +4 more
wiley   +1 more source

Neutrophil Gelatinase-associated Lipocalin, Cystatin C and Matrix Metalloproteinase-9 as Possible Biomarkers in Early Detection of Acute Kidney Injury after Cardiac Surgery [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Acute Kidney Injury (AKI) often occurs after open heart surgery. Today, serum creatinine is used as an indicator for identifying AKI; however, creatinine is unreliable due to delay in its elevation.
Sara Bagheri   +5 more
doaj   +1 more source

Identification of Proteases by Combined Fluorescent Gel Zymography and Proteomics

open access: yes, 2022
Identifying proteases and the substrate-peptides they degrade can provide valuable information to harness the enzymatic responses of specific cell types.

core  

Use of Shark Collagen for Cell Culture and Zymography [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 2002
The uses of shark collagen as a matrix for cell culture and as a substrate for zymography were investigated. Fibroblasts were cultured on a gel matrix of shark type I collagen at 30 degrees C. The collagen gel had contracted by 4 days of incubation. Individual fibroblasts were visible against the transparent background of the contracted collagen as ...
NOMURA, Yoshihiro, KITAZUME, Nobuhide
openaire   +2 more sources

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