Results 21 to 30 of about 26,894 (230)

Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) and Pulmonary Involvement in COVID-19 Pneumonia

open access: yesBiomolecules, 2023
Background: The aim of the study was to longitudinally evaluate the association between MMP-2, MMP-9, TIMP-1 and chest radiological findings in COVID-19 patients.
Maria Antonella Zingaropoli   +17 more
doaj   +1 more source

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]

open access: yes, 2017
Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup   +15 more
core   +2 more sources

Neisseria gonorrhoeae challenge increases matrix metalloproteinase-8 expression in fallopian tube explants [PDF]

open access: yes, 2017
Indexación: Scopus.Background: Neisseria gonorrhoeae (Ngo) is the etiological agent of gonorrhea, a sexually transmitted infection that initially infects the female lower genital tract.
Cristobal Muñoz   +9 more
core   +2 more sources

Evaluation of matrix metalloproteinase and cysteine cathepsin activity in dentin hybrid layer by gelatin zymography

open access: yesIndian Journal of Dental Research, 2016
Aim: The aim of this study was to comparatively assess the gelatinolytic activity of matrix metalloproteinases(MMPs) and Cysteine Cathepsins (CCs) in the adhesive interface using etch and rinse adhesive at different time intervals using zymographic ...
Sekar Mahalaxmi   +3 more
doaj   +1 more source

Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus. [PDF]

open access: yes, 2019
BackgroundDiabetic cardiomyopathy (DM CMP) is defined as cardiomyocyte damage and ventricular dysfunction directly associated with diabetes independent of concomitant coronary artery disease or hypertension.
Ahn, Jinhee   +15 more
core   +2 more sources

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

open access: yes, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Angelo Guglielmotti   +12 more
core   +13 more sources

Functional Elucidation of Nemopilema nomurai and Cyanea nozakii Nematocyst Venoms’ Lytic Activity Using Mass Spectrometry and Zymography

open access: yesToxins, 2017
Background: Medusozoans utilize explosively discharging penetrant nematocysts to inject venom into prey. These venoms are composed of highly complex proteins and peptides with extensive bioactivities, as observed in vitro.
Yang Yue   +8 more
doaj   +1 more source

Contrasting distribution of enzyme activities in the rhizosphere of European beech and Norway spruce

open access: yesFrontiers in Plant Science, 2022
Recent policies and silvicultural management call for forest regeneration that involve the selection of tree species able to cope with low soil nutrient availability in forest ecosystems.
Bin Song   +5 more
doaj   +1 more source

Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha). [PDF]

open access: yes, 2009
Matrix metalloproteinases (MMPs) have a crucial function in migration of inflammatory cells into the central nervous system (CNS). Levels of MMP-9 are elevated in multiple sclerosis (MS) and predict the occurrence of new active lesions on magnetic ...
Du, Sienmi   +6 more
core   +3 more sources

Zymography of Metalloproteinases

open access: yesCurrent Protocols in Protein Science, 2003
AbstractZymography is an electrophoretic technique enabling visualization of the number and approximate size of peptidases in a sample on the basis of their hydrolysis of a protein substrate within the gel. The technique is particularly useful for analyzing the peptidase composition of complex biological samples because visualization depends directly ...
Troeberg, L, Nagase, H
openaire   +2 more sources

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