Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
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Endothelial αvβ3 integrin induction during hypoxia protects blood-brain barrier integrity. [PDF]
Halder SK, Delorme-Walker VD, Milner R.
europepmc +1 more source
αvβ3 Integrin induces partial EMT independent of TGF-β signaling. [PDF]
Kariya Y, Oyama M, Suzuki T, Kariya Y.
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Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
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The potential role of the αVβ3 integrin receptor in placental biology and normal and complicated pregnancies. [PDF]
Rottenstreich A, Coller BS.
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Cyr61 promotes Schwann cell proliferation and migration via αvβ3 integrin. [PDF]
Cheng Z +7 more
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ABSTRACT Background Cellular Communication Network Factor 1 (CCN1) has been identified as a key regulator of oxidative stress‐induced skin aging and sensitivity. Ashwagandha root extract (ARE) is a promising candidate for modulating CCN1‐associated pathways. Aims To investigate whether ARE can mitigate sensitive‐skin aging by modulating CCN1 expression
Liying Kang +13 more
wiley +1 more source
Age-Related Dysregulation of α5β1 and αvβ3 Integrin Activity Alters Contractile Properties of Trabecular Meshwork Cells. [PDF]
Johns KL +6 more
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Human Adenovirus Type 26 Induced IL-6 Gene Expression in an αvβ3 Integrin- and NF-κB-Dependent Manner. [PDF]
Nestić D +8 more
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A DEL-1/αvβ3 integrin axis promotes brown adipocyte progenitor proliferation and cold-induced brown adipose tissue adaptation. [PDF]
Chung KJ +16 more
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