Human Adenovirus Type 26 Infection Mediated by αvβ3 Integrin Is Caveolin-1-Dependent. [PDF]
Microbiol Spectr, 2022 Nestić D, Custers J, Švec D, Majhen D.
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Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
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Peptide-Based Nanoparticles for αvβ3 Integrin-Targeted DNA Delivery to Cancer and Uterine Leiomyoma Cells. [PDF]
Molecules, 2022 Egorova A +4 more
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Cell Mechanics in Cancer: Integrating Mechanotransduction Pathways Within the Tumor Microenvironment
Journal of Cellular Physiology, Volume 241, Issue 5, May 2026.ABSTRACT Single‐cell mechanical properties such as stiffness, elasticity, and viscosity, are crucial in governing biological processes like migration, proliferation, and differentiation. In cancer, the mechanical properties of cells undergo significant alterations, which contribute to tumor growth, metastasis, and resistance to therapy.
Merve Sevgi +7 more
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Targeting Tumor Stroma: Current Challenges and Future Directions
MedComm, Volume 7, Issue 5, May 2026.Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
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Subclinical myocardial dysfunction in treatment naive papillary thyroid carcinoma patients
Scientific ReportsPapillary thyroid carcinoma (PTC) may contribute to cardiovascular (CV) morbidity through pro-inflammatory signaling and endothelial dysfunction, yet subclinical myocardial effects remain poorly characterized.
Safak Akin +6 more
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An αvβ3 integrin checkpoint is critical for efficient T<sub>H</sub>2 cell cytokine polarization and potentiation of antigen-specific immunity. [PDF]
Nat Immunol, 2023 Szeto ACH +10 more
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Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases
MedComm, Volume 7, Issue 5, May 2026.1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang +6 more
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External Stimuli‐Activable Single‐Atom Nanozymes for Bioapplications
Small, Volume 22, Issue 29, 22 May 2026.Stimuli‐activable single‐atom nanozymes (SANs) are reviewed from materials design to biomedical applications. We explain electronic‐structure tuning principles and synthesis strategies that maximize the responsiveness of metal active sites and supports to light, ultrasound, and magnetic fields.
Hyun Ko +6 more
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αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma. [PDF]
J Nanobiotechnology, 2022 Gu Y +8 more
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