Results 71 to 80 of about 143,975 (276)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Dynamic model of gene regulation for the lac operon [PDF]
, 2011 Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli ...
Asma Ben-Halim +7 more
core +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
The Conserved Dcw Gene Cluster of R. sphaeroides Is Preceded by an Uncommonly Extended 5 Leader Featuring the sRNA UpsM [PDF]
, 2016 Cell division and cell wall synthesis mechanisms are similarly conserved among bacteria. Consequently some bacterial species have comparable sets of genes organized in the dcw (division and cell wall) gene cluster.
Klug, Gabriele +5 more
core +6 more sources
Essential role for proteinase-activated receptor-2 in arthritis [PDF]
, 2003 Using physiological, pharmacological, and gene disruption approaches, we demonstrate that proteinase-activated receptor-2 (PAR-2) plays a pivotal role in mediating chronic inflammation. Using an adjuvant monoarthritis model of chronic inflammation, joint
Andrew J.H. Smith +19 more
core +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
β-Galactosidase Deficiency in Colombia
Journal of Inborn Errors of Metabolism and Screening, 2015 β-Galactosidase (BGal) is the first enzyme involved in the catabolism of sphingolipids. Two pathologies have been directly associated with its deficiency: GM1 gangliosidosis and Morquio B. Morquio B is among the rarest types of mucopolysaccharidosis (MPS)
Alfredo Uribe PhD +5 more
doaj +1 more source
Modification of β-galactosidase for use in organic mono-phase hexanol system
Macedonian Journal of Chemistry and Chemical Engineering, 2009 Different methods for preparation of the Aspergillus oryzae β-galactosidase were evaluated and the total enzyme activity was determined in hexanol mono-phase system using p-nitrophenyl-β-D-galactoside as a substrate.
Daniela Nikolovska-Nedelkoska +4 more
doaj +1 more source
Lactose hydrolysis by immobilized whole cells of K. lactis CBS 2357 : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Bioprocess Engineering at Massey University [PDF]
, 1999 The application of immobilized yeast for lactose hydrolysis was investigated. The enzyme stability was tested as a function of pretreatment. The stability of K.
Marasabessy, Ahmad
core
Synthesis of Oligosaccharides Derived from Lactulose (OsLu) Using Soluble and Immobilized Aspergillus oryzae β-Galactosidase [PDF]
, 2016 β-Galactosidase from Aspergillus oryzae offers a high yield for the synthesis of oligosaccharides derived from lactulose (OsLu) by transgalactosylation.
Batista-Viera, F. +6 more
core +4 more sources