Rapid Typing of Extended‐Spectrum β‐Lactamase (ESBL)‐ and Metallo‐β‐Lactamase (MBL)‐Producing Enterobacterales Using Fourier Transform Infrared (FT‐IR) Spectroscopy [PDF]
MicrobiologyOpenThis study investigated the usefulness of the IR Biotyper, which types bacterial strains using Fourier transform infrared (FT‐IR) spectroscopy, against extended‐spectrum β‐lactamase (ESBL)‐ and metallo‐β‐lactamase (MBL)‐producing Enterobacterales.
Yasuhide Kawamoto +9 more
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Genetic Analysis of Virulence and β-Lactamase Determinants Related to β-Lactamase Inhibitors in Pseudomonas aeruginosa Strains from Nosocomial Infections [PDF]
AntibioticsBackground/Objectives: The emergence of hypervirulent Pseudomonas aeruginosa strains resistant to β-lactamase inhibitor antibiotics is a critical health problem as they impede the treatment of infections.
Gloria Luz Paniagua-Contreras +9 more
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Whole-Cell Bioreporter-Based Assay for Detecting Fungal-Derived β-Lactamase Inhibitors [PDF]
Biosensorsβ-lactams are an important family of antibiotics that are prone to undergo resistance inhibition though the production of β-lactamases by some microorganisms.
Raz Benou +5 more
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Biochemical exploration of β-lactamase inhibitors
Frontiers in Genetics, 2023 The alarming rise of microbial resistance to antibiotics has severely limited the efficacy of current treatment options. The prevalence of β-lactamase enzymes is a significant contributor to the emergence of antibiotic resistance.
Varshaa Arer, Debasish Kar
doaj +1 more source
Frontiers in Microbiology, 2021 Objectives: Carbapenemase-producing organisms (CPOs) are associated with high mortality rates. The recent development of β-lactamase inhibitors (BLIs) has made it possible to control CPO infections safely and effectively with β-lactams (BLs).
Yanfang Feng +8 more
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TEM-E1: a novel β-lactamase conferring resistance to ceftazidime [PDF]
FEMS Microbiology Letters, 1989 A novel β-lactamase, conferring resistance to ceftazidime, has been identified to be encoded by a 31 kb plasmid (pUK720) in a clinical E. coli strain isolated in Belgium. The β-lactamase, new designated TEM-E1, has a pI of approximately 5.4 and lies in between the iso-electric focused bands of the β-lactamases TEM-1 and TEM-7.
D.J. Payne, M.S. Marriott, S.G.B. Amyes
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A β-lactamase produced by a thermophilicBacillus [PDF]
FEMS Microbiology Letters, 1996 A β-lactamase was purified from a thermophilic Bacillus strain, that had been isolated from a traditional hot bath in the Meknes area (Morocco). The properties of the enzyme were very similar to those of the β-lactamase produced by Bacillus licheniformis 749C but it exhibited a somewhat increased thermostability and a higher activation energy with ...
Fouzia Rhazi-Filali +5 more
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LXA-1: a new plasmid-mediated β-lactamase giving low-level resistance [PDF]
FEMS Microbiology Letters, 1988 LXA-1, a novel plasmid-mediated β-lactamase, was observed in clinical isolates of Klebsiella oxytoca, Klebsiella pneumoniae, Citrobacter freundii and Enterobacter cloacae. All the strains additionally produced TEM-1 β-lactamase. LXA-1 had an Mr of 24 000 and a pI of 6.7.
Youjun Yang, G.A. Jacoby, D.M. Livermore
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Distribution of β-lactamase genes of Klebsiella pneumoniae isolates in Zhejiang province, China, and regulation of gene expression [PDF]
Archives of Biological Sciences, 2017 Klebsiella pneumoniae is a common causative agent of nosocomial infections with a high level of resistance toward β-lactam antibiotics. Our previous study showed that TEM-1 and SHV-11 are the predominant β-lactamase-encoding genes of K ...
Zhao Jin-Fang +5 more
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Various Extracts of Some Medicinal Plants as Inhibitors for Beta-lactamase Activity
مجلة بغداد للعلوم, 2021 The inhibitory effect of acetone, ethanol, and aqueous extracts of ten medicinal plants on β-lactamase from Staphylococcus sciuri and Klebsiella pneumoniae was investigated in vitro by starch-iodine agar plate method.
Huda S. A. Al-Hayanni, Hamed El-Shora
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