Results 141 to 150 of about 1,489,579 (226)
Targeted faecal surveillance of conservation‐priority captive ungulates identified multidrug‐resistant nontyphoidal Salmonella and clinically relevant Enterococcus in a UAE urban zoo. These findings provide cross‐sectional baseline evidence supporting cautious integration of zoo‐based monitoring into One Health antimicrobial resistance surveillance ...
Ihab Habib +11 more
wiley +1 more source
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier +37 more
wiley +1 more source
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu +7 more
wiley +1 more source
ZnO/CuO@amoxicillin nanocomposite, synthesized via sol–gel route, demonstrates exceptional multifunctional performance. It strongly inhibits α‐amylase and α‐glucosidase, effectively suppresses inflammation, and exhibits superior antioxidant activity surpassing ascorbic acid.
Hocine Sadam Nesrat +10 more
wiley +1 more source
DFT computations are used to analyze the electronic structure, stability, and reactivity profiles of a new Schiff base ligand and its Ti(IV) complexes and are characterized by elemental analysis, IR, 1H NMR, 13C NMR, and mass spectrometry and screened for antimicrobial activities against E. coli, S. aureus, ESBL, MRSA, Mtb, A.
Priyanka Ghanghas +6 more
wiley +1 more source
Chemical composition, in vitro biological activity and in silico molecular docking of fixed oil of Linum strictum. ABSTRACT The present study investigated the fatty acid composition of Linum strictum seed oil and evaluated its antibacterial, antibiofilm, anticoagulant, and α‐amylase inhibitory activities.
Hayet Edziri +8 more
wiley +1 more source
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Phase I dose-ascending, safety, and pharmacokinetics study of APC148, a novel metallo-β-lactamase inhibitor, in healthy volunteers. [PDF]
Bolstad B +6 more
europepmc +1 more source
Multidrug‐resistant bacteria infections require alternative antimicrobial strategies. This study evaluated the phenolic composition, antibacterial activity, and in silico properties of four Moroccan monofloral honeys. Carob honey showed the greatest phenolic diversity, whereas citrus honey contained the lowest polyphenolic content.
Mourad Chikhaoui +11 more
wiley +1 more source
Plasma and intrapulmonary pharmacokinetics of funobactam, a novel diazabicyclooctane β-lactamase inhibitor, administered in combination with imipenem/cilastatin in healthy subjects. [PDF]
Rodvold K +9 more
europepmc +1 more source

