Results 31 to 40 of about 27,066 (205)

Molecular Docking Approach of Viscosin as Antibacterial for Methicillin-resistant Staphylococcus Aureus Via β-Lactamase Inhibitor Mechanism

open access: yesClinical and Research Journal in Internal Medicine, 2021
Background: β-lactamase is an enzyme that plays a role in the occurrence of antibiotic resistance against Methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Viscosin is a lipopeptide biosurfactant produced by the Pseudomonas group bacteria.
Mokhamad Fahmi Rizki Syaban   +4 more
openaire   +1 more source

Distribution and classification of Serine β-lactamases in Brazilian Hospital Sewage and Other Environmental Metagenomes deposited in Public Databases

open access: yesFrontiers in Microbiology, 2016
β-lactam is the most used antibiotic class in the clinical area and it acts on blocking the bacteria cell wall synthesis, causing cell death. However, some bacteria have evolved resistance to these antibiotics mainly due the production of enzymes known ...
Adriana Fróes   +3 more
doaj   +1 more source

Identification of Family Specific Fingerprints in β-Lactamase Families

open access: yesThe Scientific World Journal, 2014
Beta-lactamases are a superfamily of enzymes which degrade the β-lactam class of antibiotics. They are produced endogenously by the bacterial cells, which when exposed to the β-lactam class of antibiotics inactivate them by cleaving the β-lactam ring ...
Abhishikha Srivastava   +4 more
doaj   +1 more source

Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data

open access: yesMicrobiome, 2017
Background Metallo-β-lactamases are bacterial enzymes that provide resistance to carbapenems, the most potent class of antibiotics. These enzymes are commonly encoded on mobile genetic elements, which, together with their broad substrate spectrum and ...
Fanny Berglund   +7 more
doaj   +1 more source

Some aspects of general characteristic and classification of bacterial β-lactamases

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
Main structural and functional groups of bacterial β-lactamases are cited in the data review. Modern systems of classification, which was based on spectra of activity, sensitivity to inhibitors and peculiarities of molecular structure are described.
A. V. Krysenko   +2 more
doaj   +1 more source

Nucleotide sequence of the gene encoding the active-site serine β-lactamase fromStreptomyces cacaoi [PDF]

open access: yesFEMS Microbiology Letters, 1988
Abstract The gene encoding the extracellular active-site serine β-lactamase of Streptomyces cacaoi previously cloned into Streptomyces lividans , has the information for the synthesis of a 303 amino-acid precursor. The β-lactamase as excreted by the host S.
Mauro V. Lenzini   +7 more
openaire   +1 more source

Fungal Lactamases: Their Occurrence and Function

open access: yesFrontiers in Microbiology, 2017
Fungi are absorptive feeders and thus must colonize and ramify through their substrate to survive. In so doing they are in competition, particularly in the soil, with myriad microbes.
Minglu Gao   +3 more
doaj   +1 more source

Activity fingerprinting of AMR β-lactamase towards a fast and accurate diagnosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Antibiotic resistance has become a serious threat to global public health and economic development. Rapid and accurate identification of a patient status for antimicrobial resistance (AMR) are urgently needed in clinical diagnosis.
Chenchen Song   +8 more
doaj   +1 more source

Carbapenem-Resistant Klebsiella pneumoniae in Large Public Acute-Care Healthcare System, New York, New York, USA, 2016–2022

open access: yesEmerging Infectious Diseases, 2023
Controlling the spread of carbapenem-resistant Enterobacterales is a global priority. Using National Healthcare Safety Network data, we characterized the changing epidemiology of carbapenem-resistant Klebsiella pneumoniae (CRKP) in a large public health
Jennifer Lee   +7 more
doaj   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis   +5 more
wiley   +1 more source

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