Results 101 to 110 of about 740,410 (298)

Spiro-Lactams as Novel Antimicrobial Agents

, 2020
Introduction: Structural modulation of previously identified lead spiro-β-lactams with antimicrobial activity was carried out. Objective: The main objective of this work was to synthesize and evaluate the biological activity of novel spiro-lactams ...
Bártolo, Inês, Fontinha, Diana, Esteves, Margarida I. M., Melo, Teresa M. V. D. Pinho e, Soares, Maria I. L., Caratão, Cátia C., Alves, Nuno G., Alves, Américo J. S., Lopes, Susana M. M., Prudêncio, Miguel, Taveira, Nuno   +10 more
core   +1 more source

Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials

BMC Infectious Diseases, 2011
Background The emergence of multi-drug resistant Gram-negatives (MDRGNs) coupled with an alarming scarcity of new antibiotics has forced the optimization of the therapeutic potential of available antibiotics.
Van Arendonk Kyle J, Suh Yong D, Putcha Nirupama, Tamma Pranita D, Rinke Michael L   +4 more
doaj   +1 more source

Additional file 1: of Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic regimens

, 2019
Table S1. Causative pathogens of neutropenic pneumonia. (DOCX 15 kb)
Seok, Hyeri, Ko, Jae-Hoon, Peck, Kyong, Kim, Ji-Yeon, Lee, Ji, Park, Ga, Cho, Sun, Kang, Cheol-In, Lee, Nam, Chung, Doo   +9 more
openaire   +1 more source

Diastereoselectivity in Mn(III)-Promoted 4-exo-trig Cyclization of Enamides to β-Lactams

, 2016
The effect of chiral substituents on the enamide nitrogen atom upon the diastereoselection of the Mn(III)-mediated 4-exo-trig cyclization to β-lactams was studied.
Andrea DAnnibale (3076185), Floriana Umani (3076188), Corrado Trogolo (3076191), Daniele Nanni (1731088)   +3 more
core   +1 more source

The Development of the First Catalyzed Reaction of Ketenes and Imines:  Catalytic, Asymmetric Synthesis of β-Lactams

, 2016
We report practical methodology for the catalytic, asymmetric synthesis of β-lactams resulting from the development of a catalyzed reaction of ketenes (or their derived zwitterionic enolates) and imines.
Ahmed M. Hafez (2714233), Dana Ferraris (1523554), Brandon Young (470884), Harald Wack (2694217), Andrew E. Taggi (2520316), Thomas Lectka (1357518)   +5 more
core   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Additional file 2: of Rapid antimicrobial susceptibility testing and β-lactam-induced cell morphology changes of Gram-negative biological threat pathogens by optical screening

, 2018
Table S1. β-lactam-induced cell morphology changes in susceptible Burkholderia strains. (DOCX 22 kb)
McLaughlin, Heather, Sue, David
openaire   +1 more source

Catalytic, Asymmetric Synthesis of β-Lactams

, 2016
Catalytic, Asymmetric Synthesis of β ...
Ahmed M. Hafez (2714233), Brandon Young (470884), Harald Wack (2694217), Andrew E. Taggi (2520316), William J. Drury (2101174), Thomas Lectka (1357518)   +5 more
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

Animal Research and One Health, EarlyView.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista, Lucas dos Santos Janotto, Adriana Paula Possamai, Carolina Cini Perry, Francine Lemes Ribeiro, Rafael Canonenco de Araujo, Fernando Bittencourt Luciano   +6 more
wiley   +1 more source