Results 11 to 20 of about 900,428 (178)

Biosynthesis of β-nicotinamide mononucleotide from glucose via a new pathway in Bacillus subtilis [PDF]

Frontiers in Microbiology
Introductionβ-nicotinamide mononucleotide (β-NMN) is an essential precursor of nicotinamide adenine dinucleotide (NAD+) and plays a key role in supplying NAD+ and maintaining its levels.
Zhilei Tan, Yihang Yang, Yannan Wu, Jiajia Yan, Bin Zhang, Ying Hou, Shiru Jia   +6 more
doaj   +5 more sources

β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress [PDF]

Molecules
β-Nicotinamide mononucleotide (NMN) has shown promising effects on intestinal health, and it is extensively applied as an anti-aging and Alzheimer’s disease therapeutic, due to its medicinal properties. The effects of NMN on the growth of mouse hair were
Chuntao Xu, Jiawei Dai, Hongxia Ai, Weian Du, Hongbing Ji   +4 more
doaj   +4 more sources

Metabolic Engineering of Pseudomonas putida KT2440 for β-Nicotinamide Mononucleotide Biosynthesis from Glucose and Aspartate [PDF]

Microorganisms
β-Nicotinamide mononucleotide (NMN) is an important intermediate in nicotinamide adenine dinucleotide (NAD+) metabolism and has attracted increasing interest as a bioactive compound and biomanufacturing product.
Luna Gao, Lin Wei, Siqi Wang, Jun Li, Jingli Liu, Zhao Guo, Zhi-Min Li, Zhimin Li   +7 more
doaj   +4 more sources

β-Nicotinamide Mononucleotide Enhances Skin Barrier Function and Attenuates UV-B-Induced Photoaging in Mice [PDF]

Antioxidants
Ultraviolet B (UV-B) radiation significantly contributes to skin photoaging, which is characterized by epidermal thickening, collagen degradation, wrinkle formation, barrier dysfunction, and oxidative stress.
Sung Jin Kim, Sullim Lee, Yea Jung Choi, Minseo Kang, Junghwan Lee, Gwi Seo Hwang, Seok-Seon Roh, Mu Hyun Jin, Sangki Park, Minji Park, Ho Song Cho, Ki Sung Kang   +11 more
doaj   +3 more sources

β-Nicotinamide Mononucleotide Reduces Oxidative Stress and Improves Steroidogenesis in Granulosa Cells Associated with Sheep Prolificacy via Activating AMPK Pathway [PDF]

Antioxidants
Oxidative stress is a significant factor in the death of granulosa cells (GCs), leading to follicular atresia and consequently limiting the number of dominant follicles that can mature and ovulate within each follicular wave.
Yu Cai, Hua Yang, Hui Xu, Shanglai Li, Bingru Zhao, Zhibo Wang, Xiaolei Yao, Feng Wang, Yanli Zhang   +8 more
doaj   +3 more sources

Nicotinamide mononucleotide alleviates the streptozotocin-mediated ferroptosis of islet β-cells via the Nrf2/GPX4 pathway [PDF]

Brazilian Journal of Medical and Biological Research
The effects of nicotinamide mononucleotide (NMN) on streptozotocin (STZ)-induced islet β-cell dysfunction and the underlying mechanisms have not been fully elucidated.
Decheng Lu, Jianli Huang, Jinyue Meng, Jiayu Luo, Xuemei Huang   +4 more
doaj   +4 more sources

Exploring the therapeutic potential of β-nicotinamide mononucleotide (NMN) in regulating canine NT-proBNP levels [PDF]

Journal of Advanced Veterinary and Animal Research
Objectives: N-terminal pro–B-type natriuretic peptide (NT-proBNP) is a key biomarker for assessing cardiac function in companion animals and plays a critical role in the diagnosis and management of heart disease.
Zipeng Jiang, Liang Mei, Zhiyi Huang
doaj   +3 more sources

The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial [PDF]

Geroscience, 2022
In animal studies, β-nicotinamide mononucleotide (NMN) supplementation increases nicotinamide adenine dinucleotide (NAD) concentrations and improves healthspan and lifespan with great safety.
Lin Yi, A. Maier, Rong-Sheng Tao, Zhi-Gang Lin, Aditi Vaidya, Sohal Pendse, Sornaraja Thasma, Niranjan Andhalkar, Ganesh Avhad, Vidyadhar Kumbhar   +9 more
semanticscholar   +2 more sources

Effects of β-Nicotinamide Mononucleotide, Berberine, and Cordycepin on Lipid Droplet Content and Developmental Ability of Vitrified Bovine Oocytes [PDF]

Antioxidants (Basel), 2023
Oocyte vitrification is crucial for livestock reproduction, germplasm conservation, and human-assisted reproduction, but the overabundance of lipids is highly detrimental to oocyte development.
Xi Xu, Baigao Yang, Hang Zhang, Xiaoyi Feng, H. Hao, W. Du, Huabin Zhu, Adnan Khan, M. Khan, Peipei Zhang, Xueming Zhao   +10 more
semanticscholar   +2 more sources

Small extracellular vesicles derived from mesenchymal stromal cells loaded with β-nicotinamide mononucleotide activate NAD+/SIRT3 signaling pathway-mediated mitochondrial autophagy to delay skin aging [PDF]

Stem Cell Res Ther
Recently, the beneficial effects of human umbilical cord mesenchymal stromal cell (hucMSC)-derived small extracellular vesicles (sEVs) in mitigating skin aging through multiple mechanisms have been widely reported.
Zixuan Sun, Jiali Li, Yuzhou Zheng, Jiaxin Zhang, Wenhuan Bai, Xin-Yi Deng, Zhijing Wu, Xuezhong Xu, Wei Ding, Hui Qian, Yu-Lin Tan   +10 more
semanticscholar   +2 more sources