Results 121 to 130 of about 19,900 (217)

Features of the behavior of 4-amino-5-carboxamido-1,2,3-triazole in multicomponent heterocyclizations with carbonyl compounds

Beilstein Journal of Organic Chemistry, 2012
Multicomponent reactions involving polyfunctional 4-amino-5-carboxamido-1,2,3-triazole and cyclic carbonyl-containing CH-acids were studied under conventional thermal heating, microwave and ultrasonic irradiation.
Eugene S. Gladkov, Katerina A. Gura, Svetlana M. Sirko, Sergey M. Desenko, Ulrich Groth, Valentin A. Chebanov   +5 more
doaj   +1 more source

Synthesis of Functionalized 1H-Imidazoles via Denitrogenative Transformation of 5-Amino-1,2,3-Triazoles

Molecules
An efficient access to novel 2-substituted 1H-imidazole derivatives was developed based on acid-mediated denitrogenative transformation of 5-amino-1,2,3-triazole derivatives available through dipolar azide−nitrile cycloaddition (DCR).
Pavel S. Gribanov, Anna N. Philippova, Alexander F. Smol’yakov, Diana N. Tukhvatullina, Viktoria A. Vlasova, Maxim A. Topchiy, Andrey F. Asachenko, Sergey N. Osipov   +7 more
doaj   +1 more source

Biomolekuláris felismerésre képes makrociklusos receptorok szintézise = Synthesis of macrocyclic receptors capable of biomolecular recognition [PDF]

, 2013
1. Kalix-és binaftokorona éterek szintézise és alkalmazásuk 1.1. Kalix[6]arén Mitsunobu ciklizációját tanulmányoztuk 1,6-és 1,8-oktándiollal és a termékek konformációját meghatároztuk 1.2.
Bitter, István, Csókai, Viktor, Grün, Alajos   +2 more
core  

Expeditious synthesis and biological evaluation of new C-6 1,2,3-triazole adenosine derivatives A1 receptor antagonists or agonists.

, 2010
International audienceThe synthesis of new C-6 1,2,3-triazole adenosine derivatives via microwave assisted 1,3-dipolar cycloaddition as key step is described.
Attolini, Mireille, Berthault, Aurélie, By, Youlet, Carrega, Louis, Chouraqui, Gaëlle, Commeiras, Laurent, Condo, Jocelyne, Gaudel-Siri, Anouk, Guieu, Régis, Mathew, Smitha C, Parrain, Jean-Luc, Rodriguez, Jean, Ruf, Jean, Virolleaud, Marie-Alice   +13 more
core   +5 more sources

Synthesis and Evaluation of Molecular Docking and Anti-Inflammatory Activity of New 1,2,3-Triazole Derivatives

Journal of Chemistry
In this study, a series of novel substituted Ph-1,2,3-triazole derivatives 7(a–k) were synthesised via a combination of cycloaddition reactions, Click chemistry approach and Pd-catalysed Suzuki–Miyaura coupling.
Shalini Aitha, Bhookya Shankar, Raghavender Matta, Manda Srinivas, Jalapathi Pochampally   +4 more
doaj   +1 more source

Cycloaddition reactions of heterocyclic azides with 2-cyanoacetamidines as a new route to C,N-diheteroarylcarbamidines

Beilstein Journal of Organic Chemistry
A novel and efficient base-catalyzed, transition-metal-free method for the synthesis of diheterocyclic compounds connected by an amidine linker, including apart from the common 1,2,3-triazole ring, either an additional pyrimidinedione, 4-nitroimidazole ...
Pavel S. Silaichev, Tetyana V. Beryozkina, Vsevolod V. Melekhin, Valeriy O. Filimonov, Andrey N. Maslivets, Vladimir G. Ilkin, Wim Dehaen, Vasiliy A. Bakulev   +7 more
doaj   +1 more source

Synthèse, dérivation et évaluation de pharmacophores hybrides Alcynyl-TriAzolyCarbinols N-glycosylés [PDF]

, 2014
La fonction alcényl-alcynylcarbinol (AAC) est un pharmacophore clé rencontré dans des produits naturels extraits d'éponges marines, les pétrosiacétylènes, aux propriétés biologiques multiples, en particulier une cytotoxicité remarquable sur les cellules ...
Oukessou, Mohamed
core  

Design, synthesis, structural characterization, anticancer evaluation, and computational studies of novel quinoline-1,2,3-triazole glycohybrids. [PDF]

RSC Adv
Kumar R, Chauhan D, Gupta RK, Dubey PK, Kushwaha D.   +4 more
europepmc   +1 more source

Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy - a literature review. [PDF]

RSC Adv
Khasawneh HEN, Hassan HM, Alharbi AA, Almagharbeh WT, Al-Aouadi RFA, Kaur K, Maranan R, Farhan HM, Hashem H, Hassan MM, Bräse S, Al-Emam A.   +11 more
europepmc   +1 more source

Mitochondrial Dysfunction Induced by a Novel Salicylate-Based 1,2,3-Triazole Salt With Potent Antileishmanial Activity. [PDF]

Chem Biol Drug Des
De Oliveira BA, de Oliveira Lemos AS, Bastos JPRC, Antinarelli LMR, de Freitas ALR, Ribeiro RGM, da Silva Neto AF, Coimbra ES, Da Silva AD.   +8 more
europepmc   +1 more source