New reactions for the transformation of 1-(oxiranylmethyl)-1,2,3-triazoles into 2-(oxiranylmethyl)-1,2,3-triazoles or alkanenitriles were established. Successive treatment of the substrate with triflic acid and t-BuOH afforded 4,6-dihydro-5-hydroxy-1,3a,6a-triazapentalene derivative.
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ALKYLTHIOBENZOTHIAZOLES DECORATED WITH 1,2,3-TRIAZOLE
Triazole and its hybrid derivatives exhibit a range of biological activities, that is why the synthesis of hybrid heterocycles that contain triazole and benzothiazole rings is relevant. The aim of the current study is the investigation of the use of terminal butynyl and pentynyl thioethers of benzothiazole in the copper catalytic reaction of 1,3 ...
Haleha, Olha V. +3 more
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Click chemistry of phenyl 1,2,3-triazole-2-pyridylpiperazine hybrids: synthesis, targeted anticancer activity, molecular modeling and computational studies. [PDF]
El Malah T, El-Rashedy AA.
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Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy - a literature review. [PDF]
Khasawneh HEN +11 more
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The anti-angiogenic and anti-proliferative activity of n-benzoyl-3-phenyl isoserine derivative containing 1,2,3-triazole and quinoline rings. [PDF]
Hussein NR, Sahib HB, Omran ZS.
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Mitochondrial Dysfunction Induced by a Novel Salicylate-Based 1,2,3-Triazole Salt With Potent Antileishmanial Activity. [PDF]
De Oliveira BA +8 more
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Nucleophilic substitution of a phthalimidyl group with morpholine in an N<sup>1</sup>-methyl-1,2,3-triazole: crystallographic evidence for migration of the methylene bridge. [PDF]
Palme PR +5 more
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Design, synthesis, structural characterization, anticancer evaluation, and computational studies of novel quinoline-1,2,3-triazole glycohybrids. [PDF]
Kumar R +5 more
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Design, Synthesis and Antiproliferative Activity Studies of Novel 1,2,3-Triazole-Urea Hybrids. [PDF]
Gao E +11 more
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Design, synthesis, and biological properties exhibited by 1,2,3-triazole based Grp94-selective inhibitors. [PDF]
Xu H +6 more
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