Results 121 to 130 of about 61,653 (192)

Chemoselective Aldehyde and Imine Reduction by a Macrocyclic Triazole–Borane Complex Triggered by a Non‐innocent Proton–Hydride Interaction

European Journal of Organic Chemistry, Volume 29, Issue 35, 19 September 2026.
This work describes the study on a new recyclable reagent, based on a macrocyclic triazole–borane complex. It showed high chemoselectivity for aldehyde reduction and reductive amination over ketones. This selectivity is driven by a noncovalent hydride–proton interaction that stabilizes the transition state for aldehydes but is sterically inhibited in ...
Luca Di Marino, Artur Brotons Rufes, Rosaria Schettini, Giorgio Della Sala, Francesco De Riccardis, Chiara Costabile, Irene Izzo   +6 more
wiley   +1 more source

A Regioselective Approach to Accessing Trisubstituted Pyrrolo[2,3-d][1,2,3]triazoles via an Orthogonal Protection Strategy

Molecules
The first access to N-2, N-4-disubstituted pyrrolo[2,3-d][1,2,3]triazoles is reported herein. The series was generated using an orthogonal protecting group strategy from N-1, N-4-disubtituted pyrrolo[2,3-d][1,2,3]triazoles. N-Arylation by Ullman–Goldberg
Kévin Brugemann, Simon Garnier, Johnny Vercouillie, Sylvain Routier, Frédéric Buron   +4 more
doaj   +1 more source

Synthesis and Evaluation of Molecular Docking and Anti-Inflammatory Activity of New 1,2,3-Triazole Derivatives

Journal of Chemistry
In this study, a series of novel substituted Ph-1,2,3-triazole derivatives 7(a–k) were synthesised via a combination of cycloaddition reactions, Click chemistry approach and Pd-catalysed Suzuki–Miyaura coupling.
Shalini Aitha, Bhookya Shankar, Raghavender Matta, Manda Srinivas, Jalapathi Pochampally   +4 more
doaj   +1 more source

1,2,3-Triazole-linked DNA biosensors: molecular design to real-time applications. [PDF]

RSC Adv
Bhatoe G, George N, Singh G, Anshu, Singh J.   +4 more
europepmc   +1 more source

1,2,3-Triazole-Linked Chalcones as Privileged Scaffolds in Anticancer Agents. [PDF]

Arch Pharm (Weinheim)
Koldas S, Erdemir GY, Kilic A, Barlak N, Karatas OF, Altundas A.   +5 more
europepmc   +1 more source

New 1,2,3-Triazole Hybrids as Anticancer Agents: Design, Synthesis, Characterization, and In Silico Studies. [PDF]

ChemMedChem
Suárez AI, Chávez KE, Martínez P, Bubis J, Blanco Z, Ramírez H, Garmendia JV, Sanctis JB, Gurská S, Džubák P, Hajdúch M, Charris JE.   +11 more
europepmc   +1 more source

<i>Averrhoa bilimbi</i> L. Juice: An efficient natural acid catalyst for the green synthesis of dihydropyrimidinone-1,2,3-triazole. [PDF]

MethodsX
Ardiansah B, Evan J, Jumina, Santoso M, Tanimoto H, Rohman N, Cahyana AH.   +6 more
europepmc   +1 more source

Rational design, synthesis, and antimicrobial evaluation of novel 1,2,3-triazole hybrids: structure-activity relationships, molecular docking, and DFT studies. [PDF]

Sci Rep
Sallam MN, Hassan AMA, Alzahrani AYA, El-Masry HM, El-Naggar AM, Abbass EM.   +5 more
europepmc   +1 more source

Design and Synthesis of Novel 1,2,3-Triazole Conjugates Featuring Hydroxamic Acid and Sulfonamide Moieties: Exploring Dual Pharmacophores for Enhanced Biological Activity. [PDF]

Chem Biol Drug Des
Pagar D, Shaw R, Suryavanshi H, Rajani D, Patil S.   +4 more
europepmc   +1 more source

Synthesis of Novel Quinazolinone-1,2,3-Triazole Conjugates

Hybrid compounds of 2-styryl quinazolinone and 1,2,3-triazoles were synthesized via 1,3-dipolar azide-alkyne cycloaddition reaction from 3-(2-azidoethyl)quinazolinones and various alkynes, followed by Knoevenagel reaction between 2-methylquinazolinone-1 ...
Zicāne, Daina, Tetere, Zenta, Rāviņa, Irisa, Turks, Māris, Leončiks, Ainārs, Mieriņa, Inese, Krastiņa, Gerda   +6 more
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