Results 131 to 140 of about 50,268 (236)

Synthesis of Novel Quinazolinone-1,2,3-Triazole Conjugates [PDF]

Hybrid compounds of 2-styryl quinazolinone and 1,2,3-triazoles were synthesized via 1,3-dipolar azide-alkyne cycloaddition reaction from 3-(2-azidoethyl)quinazolinones and various alkynes, followed by Knoevenagel reaction between 2-methylquinazolinone-1 ...
Zicāne, Daina, Tetere, Zenta, Rāviņa, Irisa, Turks, Māris, Leončiks, Ainārs, Mieriņa, Inese, Krastiņa, Gerda   +6 more
core  

Synthesis and Evaluation of Molecular Docking and Anti-Inflammatory Activity of New 1,2,3-Triazole Derivatives

Journal of Chemistry
In this study, a series of novel substituted Ph-1,2,3-triazole derivatives 7(a–k) were synthesised via a combination of cycloaddition reactions, Click chemistry approach and Pd-catalysed Suzuki–Miyaura coupling.
Shalini Aitha, Bhookya Shankar, Raghavender Matta, Manda Srinivas, Jalapathi Pochampally   +4 more
doaj   +1 more source

ALKYLTHIOBENZOTHIAZOLES DECORATED WITH 1,2,3-TRIAZOLE

Vìsnik Dnìpropetrovsʹkogo unìversitetu. Serìâ Hìmìâ
Triazole and its hybrid derivatives exhibit a range of biological activities, that is why the synthesis of hybrid heterocycles that contain triazole and benzothiazole rings is relevant. The aim of the current study is the investigation of the use of terminal butynyl and pentynyl thioethers of benzothiazole in the copper catalytic reaction of 1,3 ...
Haleha, Olha V., Chuchvera, Yaroslav O., Ostapchuk, Eugeniy M., Onysko , Mykhailo Yu.   +3 more
openaire   +2 more sources

Transformations of 1-(Oxiranylmethyl)-1,2,3-triazoles into 2-(Oxiranylmethyl)-1,2,3-triazoles and Alkanenitriles

Transformations of 1-(Oxiranylmethyl)-1,2,3-triazoles into 2-(Oxiranylmethyl)-1,2,3-triazoles and Alkanenitriles
New reactions for the transformation of 1-(oxiranylmethyl)-1,2,3-triazoles into 2-(oxiranylmethyl)-1,2,3-triazoles or alkanenitriles were established. Successive treatment of the substrate with triflic acid and t-BuOH afforded 4,6-dihydro-5-hydroxy-1,3a,6a-triazapentalene derivative.
openaire  

Biological and In Silico Evaluation of Novel Methoxyphenol-1,2,3-Triazole Hybrids as Multifunctional Anti-Alzheimer's and Anticancer Agents. [PDF]

Chem Biol Drug Des
Onur S, Çeşme M, Tümer F.
europepmc   +1 more source

New 1,2,3-Triazole and Dipyridothiazine Hybrids-Synthesis, Analysis, Cytotoxicity and Molecular Docking. [PDF]

Biomolecules
Martula E, Bagrowska W, Strzyga-Łach P, Struga M, Latocha M, Kuśmierz D, Jeleń M, Morak-Młodawska B.   +7 more
europepmc   +1 more source

Click chemistry of phenyl 1,2,3-triazole-2-pyridylpiperazine hybrids: synthesis, targeted anticancer activity, molecular modeling and computational studies. [PDF]

RSC Adv
El Malah T, El-Rashedy AA.
europepmc   +1 more source

Current progress of 1,2,3-triazole hybrids as EGFR inhibitors for cancer therapy - a literature review. [PDF]

RSC Adv
Khasawneh HEN, Hassan HM, Alharbi AA, Almagharbeh WT, Al-Aouadi RFA, Kaur K, Maranan R, Farhan HM, Hashem H, Hassan MM, Bräse S, Al-Emam A.   +11 more
europepmc   +1 more source

The anti-angiogenic and anti-proliferative activity of n-benzoyl-3-phenyl isoserine derivative containing 1,2,3-triazole and quinoline rings. [PDF]

PLoS One
Hussein NR, Sahib HB, Omran ZS.
europepmc   +1 more source

Nucleophilic substitution of a phthalimidyl group with morpholine in an N¹-methyl-1,2,3-triazole: crystallographic evidence for migration of the methylene bridge. [PDF]

Acta Crystallogr C Struct Chem
Palme PR, Goddard R, Leutzsch M, Richter A, Imming P, Seidel RW.   +5 more
europepmc   +1 more source