Results 91 to 100 of about 20,375 (237)

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

MOF-Derived Cu@Cu2O Nanocatalyst for Oxygen Reduction Reaction and Cycloaddition Reaction [PDF]

, 2018
Research on the synthesis of nanomaterials using metal-organic frameworks (MOFs), which are characterized by multi-functionality and porosity, as precursors have been accomplished through various synthetic approaches.
Joo, Sang Hoon, Kim, Aram, Muthuchamy, Nallal, Park, Kang Hyun, Yoon, Chohye   +4 more
core   +2 more sources

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, EarlyView.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Investigation of a new bis(carboxylate)triazole-based anchoring ligand for dye-sensitised solar cell chromophore complexes [PDF]

, 2017
A novel anchoring ligand for dye-sensitised solar cell chromophoric complexes, 1-(2,2’-bipyrid-4-yl)-1,2,3-triazole-4,5-dicarboxylic acid (dctzbpy), is described. The new dye complexes [Ru(bpy)2(dctzbpy)][PF6]2 (AS16), [Ir(ppy)2(dctzbpy)][PF6] (AS17) and
Abrahamsson, Alessandro Sinopoli, Altobello, Altobello, Andrae, Ardo, Baranoff, Becke, Brennaman, Buttner, Christopher J. Wood, De Angelis, Elizabeth A. Gibson, Fallahpour, Ferrere, Fiona A. Black, Geary, Gennari, Gillaizeau-Gauthier, Goodenough, Hagfeldt, Hasselmann, Hasselmann, Heuer, Ji, Juris, Klamt, Krishnan, Lim, Lo, Lodge, Massin, Mayo, Mishra, Mishra, Murakami, Nattestad, Nazeeruddin, O'Regan, Odobel, Odobel, Paul I. P. Elliott, Pellegrin, Runge, Schweinfurth, Sinopoli, Stephens, Uppal, Valiev, Wang, Wood, Yao, Yella   +52 more
core   +1 more source

Synthesis of Novel C‐Acyl‐Glycosyl Sulfonamides via Pd‐Catalyzed Carbonylative Coupling

European Journal of Organic Chemistry, EarlyView.
A Pd‐catalyzed carbonylative coupling of 1‐iodo‐glycals with diverse sulfonamides using Mo(CO)6 enables efficient access to C‐acyl‐glycosyl sulfonamides.This robust and versatile strategy delivers novel glycoside derivatives in good to excellent yields, highlighting their potential for drug discovery.
João A. F. Silva, Mônica F. Z. J. Toledo, Flávia Manarin, João H. de Araujo‐Neto, Milene M. Hornink, Hélio A. Stefani   +5 more
wiley   +1 more source

Relative Rates of Metal-Free Azide-Alkyne Cycloadditions: Tunability over 3 Orders of Magnitude. [PDF]

, 2019
The thermal (3 + 2) dipolar azide-alkyne cycloaddition, proceeding without copper or strained alkynes, is an underutilized ligation with potential applications in materials, bioorganic, and synthetic chemistry.
Braslau, Rebecca, Kitos Vasconcelos, Ana Paula, Li, Longbo, Raskatov, Jevgenij A, Sae-Jew, Jirapon, Skelly, Patrick W, Tasnim, Jerin   +6 more
core  

Crystal Structure of 1-(2,4-dimethylphenyl)-2-(4-Trimethylsilyl-1H-1,2,3-Triazol-1-yl) Ethanone [PDF]

, 2014
The asymmetric unit of the title compound, C15H21N3OSi, contains two molecules with similar conformations (r.m.s. overlay fit for the 20 non-H atoms = 0.163 Å).
Hariprasad, S., Nagarajaiah, H., Noor Shahina Begum, ., Prasad, N.L., Venkatesh, G.B.   +4 more
core   +2 more sources

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Biological importance and synthesis of 1,2,3-triazole derivatives: a review

Green Chemistry Letters and Reviews
1,2,3-triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological activities. A number of 1,2,3-triazole-containing FDA-approved drugs are available on the market, and many other pharmaceutically significant potential ...
Mira J. Vaishnani, Sabera Bijani, Mohamed Rahamathulla, Lalji Baldaniya, Vicky Jain, Kamal Y. Thajudeen, Mohammed Muqtader Ahmed, Syeda Ayesha Farhana, Ismail Pasha   +8 more
doaj   +1 more source