Cymantrene–Triazole "Click" Products: Structural Characterization and Electrochemical Properties [PDF]
We report the first known examples of triazole-derivatized cymantrene complexes (η5-[4-substituted triazol-1-yl]cyclopentadienyl)tricarbonylmanganese(I), obtained via a “click” chemical synthesis, bearing a phenyl, 3-aminophenyl, or 4-aminophenyl moiety ...
Abboud J.-L. M. +59 more
core +1 more source
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
A administração de antimicrobianos nos casos de doenças infecciosas é inevitável, porém seu uso excessivo e indiscriminado vem influenciando na resistência bacteriana. Este cenário de saúde constitui uma extensa ameaça à população enferma e necessitada de tratamento terapêutico, o que torna necessário o empenho da comunidade científica na pesquisa e ...
Guilheane Gonçalves Barbosa +1 more
openaire +1 more source
Six norfloxacin-1,2,3-triazole hybrids(7a-e) were synthesized via click reaction. Norfloxacin-1,2,3-triazole hybrids were screened for anti-cancer activity against different cancer cell lines DLD1, MCF-7, A549 and HDF.
Samir Al-Taweel +10 more
doaj +1 more source
CuAAC-inspired synthesis of 1,2,3-triazole-bridged porphyrin conjugates: an overview
Among all the available approaches in organic synthesis, the “click chemistry” protocol is very common nowadays to covalently connect two diverse moieties in a single framework. Therefore, this review focuses on the synthesis and photophysical studies of
Dileep Kumar Singh
doaj +1 more source
Synthesis and calcium mobilization activity of cADPR analogues which integrate nucleobase, northern and southern ribose modifications [PDF]
Novel cADPR mimics, which integrate nucleobase, northern and southern ribose modifications were synthesized. The key steps of the synthesis were a Cu(I)-catalyzed Hüisgen [3+2] cycloaddition and a microwave-assisted intramolecular pyrophosphorylation ...
Jin, H +6 more
core +2 more sources
The Stabilization of High‐Nitrogen Systems: 10 Catenated Nitrogen Chain
Improving the understanding of high‐nitrogen materials. ABSTRACT High‐nitrogen materials have attracted intense interest in recent decades due to their unique chemical, physical, and biological properties. Stabilizing high‐nitrogen materials is often challenging as they become more unstable with increasing nitrogen catenation and nitrogen mass ...
Nicholas F. Scherschel +3 more
wiley +1 more source
Sensitive Energetics from the N‐Amination of 4‐Nitro‐1,2,3‐Triazole
Energetic N‐amino‐C‐nitro compounds 1‐amino‐4‐nitro‐1,2,3‐triazole and 2‐amino‐4‐nitro‐1,2,3‐triazole are characterized for the first time as energetic materials. These compounds were characterized chemically by nuclear magnetic resonance (NMR), Infrared
Dominique R. Wozniak +4 more
doaj +1 more source
One pot ‘click’ reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition [PDF]
Halohydrin dehalogenase (HheC) can perform enantioselective azidolysis of aromatic epoxides to 1,2-azido alcohols which are subsequently ligated to alkynes producing chiral hydroxy triazoles in a one-pot procedure with excellent enantiomeric excess.
Campbell-Verduyn, Lachlan S., +6 more
core +3 more sources
Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas +3 more
wiley +1 more source

