Results 51 to 60 of about 20,375 (237)

Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether

Chemistry Central Journal, 2017
Background 1,2,4-Triazoles and 1,2,3-triazoles have gained significant importance in medicinal chemistry. Results This study describes a green, efficient and quick solvent free click synthesis of new 1,2,3-triazole-4,5-diesters carrying a lipophilic side
Mohamed Reda Aouad, Mariem Mohammed Mayaba, Arshi Naqvi, Sanaa K. Bardaweel, Fawzia Faleh Al-blewi, Mouslim Messali, Nadjet Rezki   +6 more
doaj   +1 more source

Synthesis and Structure Determination of 1-(4-Methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide

Molbank, 2022
A reaction of equimolar equivalents of 1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbohydrazide (1) and indoline-2,3-dione (2) in boiling ethanol for 4 h under acidic conditions gave 1-(4-methoxyphenyl)-5-methyl-N’-(2-oxoindolin-3-ylidene)-1H-1,2 ...
Benson M. Kariuki, Bakr F. Abdel-Wahab, Abdelbasset A. Farahat, Gamal A. El-Hiti   +3 more
doaj   +1 more source

Synthesis of N1 and N2 coumarin substituted 1,​2,​3-​triazole isomers via click chemistry approach [PDF]

, 2016
The synthesis of N1 and N2 coumarin substituted 1,​2,​3-​triazole isomers from terminal alkynes, sodium azide, and 4-​bromomethylcoumarins in the presence of triethylamine as a base and CuI as a catalyst in good yield were reported. The mol.
Chandra, ., Mahendra Madegowda, ., Shamala Devadas, ., Shivashankar Kalegowda, .   +3 more
core   +1 more source

Deprotometalation-iodolysis and computed CH acidity of 1,2,3- and 1,2,4-triazoles. Application to the synthesis of resveratrol analogues

, 2015
International audience1-Aryl- and 2-aryl-1,2,3-triazoles were synthesized by N-arylation of the corresponding azoles using aryl iodides. The deprotometalations of 1-phenyl-1,2,3-triazole and -1,2,4-triazole were performed using a 2,2,6,6 ...
Bentabed-Ababsa, Ghenia, Chevallier, Floris, Duval, Raphaël E., Fontanay, Stéphane, Halauko, Yury S., Ivashkevich, Oleg A., Matulis, Vadim E., Mongin, Florence, Nagaradja, Elisabeth, Phillipot, Stéphanie, Roisnel, Thierry, Scalabrini, Mathieu   +11 more
core   +3 more sources

Synthesis, Spectroscopic Analysis, and In Vitro Anticancer Evaluation of 2-(Phenylsulfonyl)-2H-1,2,3-triazole

Molbank, 2022
The 1,2,3-Triazole derivatives containing the sulfonyl group have proved their biological importance in medicinal chemistry and drug design. In this sense, we describe the regioselective synthesis of 2-(phenylsulfonyl)-2H-1,2,3-triazole 3 in good yield ...
Angélica Salinas-Torres, Jaime Portilla, Hugo Rojas, Diana Becerra, Juan-Carlos Castillo   +4 more
doaj   +1 more source

Multicomponent Azide-Alkyne Cycloaddition Catalyzed by Impregnated Bimetallic Nickel and Copper on Magnetite [PDF]

, 2014
A new bimetallic catalyst derived from nickel and copper has been used successfully for the first time in the multicomponent reaction of terminal alkynes, sodium azide, and benzyl bromide derivatives.
Cano Monserrat, Rafael, Pérez Galera, Juana María, Ramón, Diego J.   +2 more
core   +2 more sources

1,2,3-Triazole: an important scaffold in drug design and development

Heterocyclic Communications
1,2,3-triazole represents a class of nitrogen-containing heterocyclics with a wide range of biological activity. The medicinal applications of 1,2,3-triazole derivatives, including antioxidant, antimicrobial, antiviral, anti-inflammatory, antitumor, and ...
Alghamdi Danyah Y., Zailaee Rasha A., Al-Amshany Zahra M., El-Shishtawy Reda M.   +3 more
doaj   +1 more source

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety

Molecules, 2017
In this study, 1-(5-Methyl-1-(p-tolyl)-1H-1,2,3-triazol-4-yl)ethan-1-one, was reacted with Thiosemicarbazide, alkyl carbodithioate and benzaldehyde to give thiosemicarbazone, alkylidenehydrazinecarbodithioate and 3-phenylprop-2-en-1-one-1,2,3-triazole ...
Nadia A. Abdelriheem, Ali M. M. Mohamed, Abdou O. Abdelhamid   +2 more
doaj   +1 more source

Kinetic and Thermodynamic Approaches for the Efficient Formation of Mechanical Bonds [PDF]

, 2008
Among the growing collection of molecular systems under consideration for nanoscale device applications, mechanically interlocked compounds derived from electrochemically switchable bistable [2]rotaxanes and [2]catenanes show great promise. These systems
Aprahamian, Ivan, Dichtel, William R., Heath, James R., Miljanić, Ognjen Š., Patel, Kaushik, Spruell, Jason M., Stoddart, J. Fraser, Zhang, Wenyu   +7 more
core   +1 more source

High‐Power Rapid Laser‐Induced Synthesis of Multi‐functional Cobalt Metal‐Organic Framework With an Unprecedented Synthesis Efficiency

Advanced Materials Technologies, EarlyView.
Laser‐assisted synthesis enables rapid (within 1 h) and high‐yield (≥90%) production of Co‐MOFs with mesoporous structures, tunable magnetic and optical properties, and efficient adsorption of N2, CH4, and CO2 for low‐energy gas separation. DFT calculations elucidate the electronic structure and adsorption behavior.
Saliha Mutlu, Bülend Ortaç, Ali Karatutlu, Taylan Gorkan, Engin Durgun, Dilek Soyler, Saniye Soylemez, Jelena Lillepäg, Volkan Filiz, Nergis Arsu, Sevil Savaskan Yilmaz   +10 more
wiley   +1 more source