Results 51 to 60 of about 50,236 (242)

Synthesis of Ribosylated 1,2,3‐Triazole Derivatives.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Zhong‐Xu Ren, Xiao‐Min Chen, Zhan‐Jiang Li, Zhi‐Tang Huang   +3 more
openaire   +1 more source

A Chemically Defined Four‐Component Self‐Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity

Advanced Science, EarlyView.
A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming, Renyu Zhang, Xiaohui Li, Guiqi Li, Yu Niu, Deying Yang, Xiang Luo, Jun Liao, Zhongqiu Liu, Guochao Liao   +9 more
wiley   +1 more source

SÍNTESE E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE DERIVADOS DO EUGENOL CONTENDO NÚCLEOS 1,2,3-TRIAZÓLICOS

Química Nova
Eugenol is an aromatic compound found in several plant species. It presents important biological activities including cytotoxicity. In this paper, it is described the synthesis and the evaluation of the cytotoxic activity of eugenol derivatives bearing 1,
Poliana Aparecida Rodrigues Gazolla, Róbson Ricardo Teixeira, Adalberto Manoel da Silva, Boniek Gontijo Vaz, Géssica Adriana Vasconcelos, Raoni Pais Siqueira, Victor Hugo Sousa Gonçalves, Higor Sette Pereira, Gustavo Costa Bressan   +8 more
doaj   +1 more source

Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactors

, 2011
Synthesis of 1,2,3-triazole moiety-containing NAD analogs and their potential as redox cofactorsThirteen 1,2,3-triazole moiety-containing NAD analogs were synthesized and evaluated as redox cofactors.
赵宗保, Zhao, Zongbao Kent, Hou, Shuhua, Wang, Qian, Ji, Debin, Liu, Wujun   +5 more
core   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, EarlyView.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Synthesis, Spectroscopic Analysis, and In Vitro Anticancer Evaluation of 2-(Phenylsulfonyl)-2H-1,2,3-triazole

Molbank, 2022
The 1,2,3-Triazole derivatives containing the sulfonyl group have proved their biological importance in medicinal chemistry and drug design. In this sense, we describe the regioselective synthesis of 2-(phenylsulfonyl)-2H-1,2,3-triazole 3 in good yield ...
Angélica Salinas-Torres, Jaime Portilla, Hugo Rojas, Diana Becerra, Juan-Carlos Castillo   +4 more
doaj   +1 more source

Cristais líquidos termotrópicos calamíticos contendo o heterociclo [1,2,3]-triazol 1,4-dissubstituído [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaA síntese e as propriedades térmicas de cinco séries homólogas de compostos calamíticos lineares e não lineares,
Santos, Deise Maria Pereira de Oliveira
core  

Cu(OTf)₂-Catalyzed 1,2,3-triazole-ring-controlled selective phenolic O–H bond methylthiomethylation

, 2019
Copper-catalyzed selective methylthiomethylation of 1,4-disubstituted 1,2,3-triazole phenols using DMSO as a methylthiomethylation reagent was achieved.
Weigen Du (6918761), Yubo Jiang (4426555), Huiling Cheng (2898452), Xinyuan Ma (5262572), Wei Liu (20030)   +4 more
core   +1 more source

Introducing Axial Chirality into Mesoionic 4,4′-Bis(1,2,3-triazole) Dicarbenes [PDF]

, 2012
Mesoionic 4,4′-bis(1,2,3-triazole-5,5′-diylidene) Rh(I) complexes having a C2 chiral 4,4′-axis were accessed from 3-alkyltriazolium salts in virtually complete de.
Monasterio, Zaira, Mendicute, Claudio, Azcune, Itxaso, García-Lecina, Eva, Monasterio, Z., Altube, Ainhoa, Aizpurua, J.M., Sagartzazu-Aizpurua, Maialen, Fratila, Raluca M., Azcune, I., Mendicute, C., Garcia-Lecina, E., Altube, A., Miranda, J.I., Fratila, R.M., Sagartzazu-Aizpurua, M., Aizpurua, Jesús M., Miranda, José Ignacio   +17 more
core   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source