Results 31 to 40 of about 50,236 (242)

1,2,3-Triazoles

, 2008
Rapid progress in the synthetic application of benzotriazole derivatives in the last 20 years has resulted in over 1000 scientific papers on the subject. This fact is reflected in Section 5.01.7, which involves almost a half of the volume of this chapter. The section is arranged according to hybridization of the C-α atom and atomic numbers of the atoms
Rachwal, S., Katritzky, A.R.
openaire   +1 more source

Synthesis and Antiproliferative Evaluation of Novel Hybrids of Dehydroabietic Acid Bearing 1,2,3-Triazole Moiety

Molecules, 2019
To discover novel potent cytotoxic diterpenoids, a series of hybrids of dehydroabietic acid containing 1,2,3-triazole moiety were designed and synthesized.
Fang-Yao Li, Lin Huang, Qian Li, Xiu Wang, Xian-Li Ma, Cai-Na Jiang, Xiao-Qun Zhou, Wen-Gui Duan, Fu-Hou Lei   +8 more
doaj   +1 more source

Water/Alkali-Catalyzed Reactions of Azides with 2‑Cyanothioacetamides. Eco-Friendly Synthesis of Monocyclic and Bicyclic 1,2,3-Thiadiazole-4-carbimidamides and 5‑Amino-1,2,3-triazole-4-carbothioamides

, 2019
The reactions of thioamides with azides in water were studied. It was reliably shown that the reaction of 2-cyanothioacetamides 1 with various types of azides 2 in water in the presence of alkali presents an efficient, general, one-step, atom-economic ...
Nikolai A. Beliaev (7461455), Lidia N. Dianova (3901567), Wim Dehaen (496141), Albert T. Lebedev (1778380), Vladimir G. Ilkin (7461461), Valeriy O. Filimonov (3901573), Natalia N. Volkova (7461458), Tetyana V. Beryozkina (3901576), Dmitrii Mazur (7461452), Vasiliy A. Bakulev (3043827)   +9 more
core   +4 more sources

Design and Antiproliferative Evaluation of Novel Sulfanilamide Derivatives as Potential Tubulin Polymerization Inhibitors

Molecules, 2017
A series of sulfanilamide-1,2,3-triazole hybrids were designed by a molecular hybridization strategy and evaluated for antiproliferative activity against three selected cancer cell lines (MGC-803, MCF-7 and PC-3).
Dong-Jun Fu, Ji-Feng Liu, Ruo-Han Zhao, Jia-Huan Li, Sai-Yang Zhang, Yan-Bing Zhang   +5 more
doaj   +1 more source

Radiosynthesis of 5-[¹⁸F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[¹⁸F]Fluorine Exchange Reaction

Molecules, 2021
In this report, a simple and efficient process to achieve fluorine-18-labeled 1,2,3-triazole is reported. The heteroaromatic radiofluorination was successfully achieved through an iodine–fluorine-18 exchange in an aqueous medium requiring only trace ...
Xiang Zhang, Falguni Basuli, Sameh Abdelwahed, Tadhg Begley, Rolf Swenson   +4 more
doaj   +1 more source

Enzymatic Macrocyclization of 1,2,3‐Triazole Peptide Mimetics [PDF]

Angewandte Chemie International Edition, 2016
AbstractThe macrocyclization of linear peptides is very often accompanied by significant improvements in their stability and biological activity. Many strategies are available for their chemical macrocyclization, however, enzyme‐mediated methods remain of great interest in terms of synthetic utility.
Emilia Oueis, Marcel Jaspars, Nicholas J. Westwood, James H. Naismith   +3 more
openaire   +6 more sources

Photochemical ligand ejection from non-sterically promoted Ru(ii)bis(diimine) 4,4′-bi-1,2,3-triazolyl complexes

, 2014
Complexes of the form [Ru(diimine)2(btz)]2+ (btz = 1,1′-dibenzyl-4,4′-bi-1,2,3-triazolyl) are observed to undergo photochemical ejection of the btz ligand in the absence of any promotion through steric congestion to generate cis-bis(solvent) complexes ...
Sinopoli, Alessandro, Uppal, Baljinder S., Welby, Christine E., Bartley, Harry, Armitage, Georgina K., Elliott, Paul I P, Elliott, Paul I.   +6 more
core   +1 more source

Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether

Chemistry Central Journal, 2017
Background 1,2,4-Triazoles and 1,2,3-triazoles have gained significant importance in medicinal chemistry. Results This study describes a green, efficient and quick solvent free click synthesis of new 1,2,3-triazole-4,5-diesters carrying a lipophilic side
Mohamed Reda Aouad, Mariem Mohammed Mayaba, Arshi Naqvi, Sanaa K. Bardaweel, Fawzia Faleh Al-blewi, Mouslim Messali, Nadjet Rezki   +6 more
doaj   +1 more source

Synthesis of Biologically Relevant 1,2,3- and 1,3,4-Triazoles: From Classical Pathway to Green Chemistry

Molecules, 2021
Green Chemistry has become in the last two decades an increasing part of research interest. Nonconventional «green» sources for chemical reactions include micro-wave, mechanical mixing, visible light and ultrasound.
Lori Gonnet, Michel Baron, Michel Baltas
doaj   +1 more source

Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition

, 2011
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Krim, Jamal, Taourirte, Mohamed, Engels, Joachim W., Moha Taourirte, Jamal Krim, Joachim W. Engels   +5 more
core   +1 more source