Results 11 to 20 of about 8,430 (199)
1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety.
Tomas Opsomer +3 more
doaj +1 more source
Reaction of 4-acetyl-1,2,3-triazol-5-olate with hydrazine derivatives
1,2,3-triazole attracts attention because of the ability opening ring to form α-diazoimin and intramolecular rearrangements with the formation of various heterocyclic systems.
I. S. Khazhieva +2 more
doaj +1 more source
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin +7 more
doaj +1 more source
One-Pot Synthesis of Tetrazole–Triazole Bis-Heterocycles via Ugi–Azide Reaction
Bioisosteres of amide bonds such as 4,5-disubstituted-1,2,3-triazoles (4,5-DS-1,2,3-Ts) and 1,5-disubstituted tetrazoles (1,5-DST) are present in compounds with important biological activities like those that are antineoplastic, antibacterial, antifungal,
Fidel Rodriguez-Lopez +3 more
doaj +1 more source
Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids [PDF]
Aim: The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-triazole hybrids, inspired by previously identified bioactive ...
David Chafi Zeitune +6 more
doaj +1 more source
Antiproliferative Phenothiazine Hybrids as Novel Apoptosis Inducers against MCF-7 Breast Cancer
We designed a series of novel phenothiazine-1,2,3-triazole hybrids by the molecular hybridization strategy and evaluated their antiproliferative activity against three cancer cell lines (MDA-MB-231, MDA-MB-468 and MCF-7).
Jun-Xia Zhang +7 more
doaj +1 more source
Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate
We have previously published new biheterocyclic phospohonic α-amino esters of the 1,2,3-triazole-benzimidazole and 1,2,3-triazole-carbazole type. The aim of the present paper was to describe a new phosponic aminoester bearing a triazole ring substituted ...
Serigne Abdou Khadir Fall +8 more
doaj +1 more source
Three-component synthesis of 1,2,3-triazoles in the presence of PVC-supported triazole-copper complex by click reaction [PDF]
In this research work novel PVC-supported triazole-copper(I) iodide catalyst (PVC–Triazole–CuI) was prepared and used the for synthesis of 1,2,3-triazoles.
Ali Keivanloo +2 more
doaj +1 more source
Click Chemistry Approach to Isoindole-1,3-dione Tethered 1,2,3-Triazole Derivatives
A convenient and efficient approach for the synthesis of novel 1,2,3-triazole tethered isoindol-1,3-dione conjugates by a nucleophilic substitution reaction of phthalic anhydride with 1,2,3-triazole containing carbohydrazide is described. The latter were
Rajneesh Kaur +3 more
doaj +1 more source
(1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate 3-(4-hydroxymethyl-1H-1,2,3-triazol-1-yl)quinoline-2,4(1H,3H)-diones unsubstituted on quinolone ...
Milićević, David +5 more
openaire +5 more sources

