Three-component synthesis of 1,2,3-triazoles in the presence of PVC-supported triazole-copper complex by click reaction [PDF]
In this research work novel PVC-supported triazole-copper(I) iodide catalyst (PVC–Triazole–CuI) was prepared and used the for synthesis of 1,2,3-triazoles.
Ali Keivanloo +2 more
doaj +1 more source
Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA. [PDF]
Amidinobenzimidazole derivatives connected to 1-aryl-substituted 1,2,3-triazole through phenoxymethylene linkers 7a-7e, 8a-8e, and 9a-9e were designed and synthesised with the aim of evaluating their anti-bacterial and anti-trypanosomal activities and ...
Bajić, Miroslav +8 more
core +2 more sources
Synthesis of 1,2,3-triazole functionalized hyperbranched poly(ethyleneimine) and its use as multifunctional anionic macroinitiator for diglycidyl ether of bisphenol A curing [PDF]
Hyperbranched poly(ethyleneimine) (PEI) has been modified by the addition of propargyl acrylate following a Michael addition reaction. On this polymer (PEI-yne) a copper (I)-catalyzed azide alkyne cycloaddition (CuAAC) has been performed to obtain a ...
Acebo Gorostiza, Cristina +4 more
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Lung cancer is the most common malignancy and leads to around one-quarter of all cancer deaths. Great advances have been achieved in the treatment of lung cancer with novel anticancer agents and improved technology. However, morbidity and mortality rates
Ting Liang +4 more
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Reactivity of (1-methoxycarbonylpentadienyl)iron(1+) cations with hydride, methyl, and nitrogen nucleophiles [PDF]
The reaction of tricarbonyl and (dicarbonyl)triphenylphosphine (1-methoxycarbonyl-pentadientyl)iron(1+) cations 7 and 8 with methyl lithium, NaBH3CN, or potassium phthalimide affords (pentenediyl)iron complexes 9a-c and 11a-b, while reaction with ...
Anobick Sar +58 more
core +2 more sources
Click Chemistry Approach to Isoindole-1,3-dione Tethered 1,2,3-Triazole Derivatives
A convenient and efficient approach for the synthesis of novel 1,2,3-triazole tethered isoindol-1,3-dione conjugates by a nucleophilic substitution reaction of phthalic anhydride with 1,2,3-triazole containing carbohydrazide is described. The latter were
Rajneesh Kaur +3 more
doaj +1 more source
Synthesis and In Vitro Anticancer Evaluation of Flavone—1,2,3-Triazole Hybrids
Hybrid compounds of flavones, namely chrysin and kaempferol, and substituted 1,2,3-triazole derivatives, were synthesized by click reaction of the intermediate O-propargyl derivatives.
Alexandra Németh-Rieder +5 more
doaj +1 more source
8-Azaguanine (1) is a special 1,2,3-triazole containing natural product that possesses potent antibacterial and antitumor activities. In the present study, the entire 8-azaguanine biosynthetic gene cluster was located from Streptomyces CGMCC4.1633 ...
Feifei Hou +6 more
doaj +1 more source
A series of 1H-1,2,3-triazole analogs (7a–7d and 9a–9s) were synthesized via “click” chemistry and evaluated for in vitro carbonic anhydrase-II (bovine and human) inhibitory activity. The synthesis of intermediates, 7a and 7c, was achieved by using (S)-(-
Majid Khan +7 more
doaj +1 more source
Copper(I)-N-heterocyclic carbene complexes as efficient catalysts for the synthesis of 1,4-disubstituted 1,2,3-sulfonyltriazoles in air [PDF]
Bis-NHC and mixed NHC/PR3 copper(I) complexes (NHC = N-heterocyclic carbene) were found to be efficient catalysts enabling the azide-alkyne cycloaddition reaction leading to the formation of 1,2,3-sulfonyltriazoles under Click conditions.
Cazin, Catherine, Lazreg, Faïma
core +2 more sources

