Results 21 to 30 of about 7,707 (195)
1,2,3-Triazoles: Controlled Switches in Logic Gate Applications
Sensors, 2023 A 1,2,3-triazole-based chemosensor is used for selective switching in logic gate operations through colorimetric and fluorometric response mechanisms. The molecular probe synthesized via “click chemistry” resulted in a non-fluorescent 1,4-diaryl-1,2,3-triazole with a phenol moiety (PTP).
Debanjana Ghosh +7 more
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Antiproliferative Phenothiazine Hybrids as Novel Apoptosis Inducers against MCF-7 Breast Cancer
Molecules, 2018 We designed a series of novel phenothiazine-1,2,3-triazole hybrids by the molecular hybridization strategy and evaluated their antiproliferative activity against three cancer cell lines (MDA-MB-231, MDA-MB-468 and MCF-7).
Jun-Xia Zhang +7 more
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Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate
Molbank, 2021 We have previously published new biheterocyclic phospohonic α-amino esters of the 1,2,3-triazole-benzimidazole and 1,2,3-triazole-carbazole type. The aim of the present paper was to describe a new phosponic aminoester bearing a triazole ring substituted ...
Serigne Abdou Khadir Fall +8 more
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Three-component synthesis of 1,2,3-triazoles in the presence of PVC-supported triazole-copper complex by click reaction [PDF]
شیمی کاربردی روز, 2020 In this research work novel PVC-supported triazole-copper(I) iodide catalyst (PVC–Triazole–CuI) was prepared and used the for synthesis of 1,2,3-triazoles.
Ali Keivanloo +2 more
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Acta Chimica Slovenica, 2020 (1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate 3-(4-hydroxymethyl-1H-1,2,3-triazol-1-yl)quinoline-2,4(1H,3H)-diones unsubstituted on quinolone ...
Milićević, David +5 more
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Click Chemistry: 1,2,3‐Triazoles as Pharmacophores [PDF]
Chemistry – An Asian Journal, 2011 AbstractThe copper(I)‐catalyzed 1,2,3‐triazole‐forming reaction between azides and terminal alkynes has become the gold standard of ‘click chemistry’ due to its reliability, specificity, and biocompatibility. Applications of click chemistry are increasingly found in all aspects of drug discovery; they range from lead finding through combinatorial ...
Suleman R. Maujan +2 more
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Frontiers in Pharmacology, 2021 Lung cancer is the most common malignancy and leads to around one-quarter of all cancer deaths. Great advances have been achieved in the treatment of lung cancer with novel anticancer agents and improved technology. However, morbidity and mortality rates
Ting Liang +4 more
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Synthesis and In Vitro Anticancer Evaluation of Flavone—1,2,3-Triazole Hybrids
Molecules, 2023 Hybrid compounds of flavones, namely chrysin and kaempferol, and substituted 1,2,3-triazole derivatives, were synthesized by click reaction of the intermediate O-propargyl derivatives.
Alexandra Németh-Rieder +5 more
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Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker [PDF]
Molecules, 2015 A novel series of {4-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates and {4-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates as acyclic analogues of guanosine were synthesized and assessed for antiviral activity against a broad range of DNA and RNA viruses and for their ...
Głowacka, Iwona E. +4 more
openaire +6 more sources
Click Chemistry Approach to Isoindole-1,3-dione Tethered 1,2,3-Triazole Derivatives
SynOpen, 2019 A convenient and efficient approach for the synthesis of novel 1,2,3-triazole tethered isoindol-1,3-dione conjugates by a nucleophilic substitution reaction of phthalic anhydride with 1,2,3-triazole containing carbohydrazide is described. The latter were
Rajneesh Kaur +3 more
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