Results 101 to 110 of about 11,801 (209)

Self-healing metallo-supramolecular hydrogel based on specific Ni2+ coordination interactions of poly(ethylene glycol) with bistriazole pyridine ligands in the main chain [PDF]

, 2020
In this study, a supramolecular hydrogel formed by incorporating the 2,6-bis(1,2,3-triazol-4-yl)-pyridine (btp) ligand in the backbone of a polymer prepared by copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) "click" polyaddition reaction of 2,6 ...
Hoogenboom, Richard, Jerca, Valentin-Victor, Xu, Xiaowen   +2 more
core   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Combined XRD-paramagnetic 13C NMR spectroscopy of 1,2,3-triazoles for revealing copper traces in a Huisgen click-chemistry cycloaddition. A model case

Heterocyclic Communications, 2019
Copper-catalyzed Alkyne-Azide Cycloaddition (CuAAC) click chemistry robustness has been demonstrated over recent years to produce 1,2,3-triazoles with excellent yields at mild conditions with simple purification methods.
Canseco-González Daniel, O José Luis Rodríguez de la, Herbert-Pucheta José Enrique   +2 more
doaj   +1 more source

Enantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles

Nature Communications
Chiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challenge, mainly due to the limited catalytic ...
Ling-Feng Jiang, Shao-Hua Wu, Yu-Xuan Jiang, Hong-Xiang Ma, Jia-Jun He, Yang-Bo Bi, De-Yi Kong, Yi-Fei Cheng, Xuan Cheng, Qing-Hai Deng   +9 more
doaj   +1 more source

Azide-Alkyne Huisgen [3+2] Cycloaddition Using CuO Nanoparticles [PDF]

, 2012
Recent developments in the synthesis of CuO nanoparticles (NPs) and their application to the [3+2] cycloaddition of azides with terminal alkynes are reviewed.
Alonso, Alonso, Aram Kim, Byeong-Su Kim, Casavola, Cintas, Gupta, Hyunje Woo, Hyunjoon Song, Hyuntae Kang, Ji Park, Kang Park, Kim, Lee, Orgueira, Park, Seongwan Jang, Somorjai, Sungkyun Park, Zhang   +19 more
core   +2 more sources

Ligand synthesis catalyst and complex metal ion: multicomponent synthesis of 1,3-bis(4-phenyl-[1,2,3]triazol-1-yl)-propan-2-ol copper(i) complex and application in copper-catalyzed alkyne-azide cycloaddition [PDF]

, 2016
A new bistriazole copper complex was synthesized by direct treatment of an alkyne, an azide, and CuI as copper salt through in situ ligand formation under a multicomponent reaction process. This complex was analyzed by XPS, TGA, DSC, and SEM techniques
CUEVAS YAÑEZ, ERICK, CUEVAS YAÑEZ, ERICK, LOPEZ TELLEZ, GUSTAVO, LOPEZ TELLEZ, GUSTAVO, RAMIREZ PALMA, MARIA TERESA, RAMIREZ PALMA, MARIA TERESA, Segura Arzate, Jesús, Segura Arzate, Jesús   +7 more
core  

[1-(2,5-Dichloroanilino)-5-methyl-1H-1,2,3-triazol-4-yl]methanol [PDF]

, 2016
In the title compound, C10H10Cl2N4O, the hy­droxy group and benzene ring are disposed to opposite sides of the central 1,2,3-triazolyl ring. The dihedral angle between the five- and six-membered rings is 87.51 (12)°, and the C-O bond of the hy­droxy ...
Almeida, Maria C. B. de, Cunha, Anna C., Ferreira, Vitor F., Jordão, Alessandro K., Souza, Maria C. B. V. de, Tiekink, Edward R. T. *, Wardell, James L.   +6 more
core   +2 more sources

Azide–alkyne cycloaddition (click) reaction in biomass-derived solvent CyreneTM under one-pot conditions

Beilstein Journal of Organic Chemistry
It was demonstrated that CyreneTM, as a biomass-originated polar aprotic solvent, could be utilized as an alternative reaction medium for one-pot copper(I)-catalyzed azide–alkyne cycloaddition (click or CuAAC) reactions, for the synthesis of various 1,2 ...
Zoltán Medgyesi, László T. Mika
doaj   +1 more source

Synthesis of 6-Amino-5-cyano-1,4-disubstituted-2(1H)-Pyrimidinones via Copper-(I)-catalyzed Alkyne-azide ‘Click Chemistry’ and Their Reactivity

Molecules, 2010
In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3 + 2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presence of
Fethi Zribi, Romain Duval, Fakher Chabchoub, Françoise Nepveu, Ennaji Najahi, Jan Sudor   +5 more
doaj   +1 more source

Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]

, 2015
The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy, Jin, Liqun, Melaimi, Mohand, Tolentino, Daniel R   +3 more
core   +2 more sources