Results 31 to 40 of about 11,801 (209)
Well-Defined Diimine Copper(I) Complexes as Catalysts in Click Azide-Alkyne Cycloaddition Reactions [PDF]
, 2013 A series of 1,4-disubstituted 1,2,3-triazoles have been prepared in high yields while respecting the stringent Click criteria.
Diez-Gonzalez, S, Markalain Barta, J
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Microwave assisted metal-free approach to access 1,2,3-triazoles through multicomponent synthesis
Current Research in Green and Sustainable Chemistry, 2020 The work illustrates multicomponent reaction of aldehydes, nitroalkanes and sodium azide for the metal-free synthesis of N-unsubstituted-1,2,3-triazoles using anthranilic acid as an organocatalyst under microwave irradiation. This is the first ever green
Anirban Garg +2 more
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Anais da Academia Brasileira de Ciências, 2021 This study describes the synthesis and antioxidant activity of new 1,4-disubstituted 1,2,3-triazoles. These compounds were generated semi-synthetically using the Cu(I)-catalysed azide-alkyne cycloaddition (CuAAC) reaction between ethyl 2-azidoacetate and
JOSEFA A. DA CUNHA LIMA +6 more
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Click Chemistry: 1,2,3‐Triazoles as Pharmacophores [PDF]
Chemistry – An Asian Journal, 2011 AbstractThe copper(I)‐catalyzed 1,2,3‐triazole‐forming reaction between azides and terminal alkynes has become the gold standard of ‘click chemistry’ due to its reliability, specificity, and biocompatibility. Applications of click chemistry are increasingly found in all aspects of drug discovery; they range from lead finding through combinatorial ...
Sandip G, Agalave +2 more
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1,2,3-Triazoles as Amide-bond Surrogates in Peptidomimetics
CHIMIA, 2013 1,2,3-Triazoles represent a class of heterocycles with interesting properties for application in peptide sciences since they closely resemble amide bonds while being stable to enzymatic degradation.
Ibai E. Valverde, Thomas L. Mindt
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Enantiomer stability of atropisomeric 1,5-disubstituted 1,2,3-triazoles
Tetrahedron Chem, 2022 The synthesis and characterisation of axially chiral atropisomeric 1,5-disubstituted 1,2,3-triazoles is reported. Molecules designed to display restricted rotation about 1,2,3-triazole N-1-aryl or 1,2,3-triazole C-5-aryl bonds were investigated by ...
Fernanda Meloni +6 more
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, 2008 Rapid progress in the synthetic application of benzotriazole derivatives in the last 20 years has resulted in over 1000 scientific papers on the subject. This fact is reflected in Section 5.01.7, which involves almost a half of the volume of this chapter. The section is arranged according to hybridization of the C-α atom and atomic numbers of the atoms
Rachwal, S., Katritzky, A.R.
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Glycerol: a biorenewable solvent for base-free Cu(I)-catalyzed 1,3-dipolar cycloaddition of azides with terminal and 1-iodoalkynes. Highly efficient transformations and catalyst recycling [PDF]
, 2014 Ministerio de Ciencia e Innovacin (MICINN) of Spain [CTQ2010-14796, RYC-2011-08451]; MICINN; European Social ...
García Álvarez, Joaquín +1 more
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The Scientific World Journal, 2013 A library of 1,2,3-triazoles was synthesized from diverse alkynes and azides using catalytic amounts of silver chloride instead of copper compounds. In addition, a novel “abnormal” silver N-heterocyclic carbene complex was tested as catalyst in this ...
Aldo I. Ortega-Arizmendi +2 more
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Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
Molecules, 2016 Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.
Chengwei Zhang, Lin You, Chuo Chen
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