Results 21 to 30 of about 34,622 (239)
Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives [PDF]
International Journal of Molecular Sciences, 2021 The worldwide development of antimicrobial resistance forces scientists to search for new compounds to which microbes would be sensitive. Many new structures contain the 1,3,4-oxadiazole ring, which have shown various antimicrobial activity, e.g., antibacterial, antitubercular, antifungal, antiprotozoal and antiviral. In many publications, the activity
Teresa Glomb, Piotr Świątek
openaire +2 more sources
Synthesis and Biological Activity of 1,3,4-Oxadiazoles Used in Medicine and Agriculture
Applied Sciences, 2022 Biologically active compounds play a key role in the fight against diseases affecting both human and animal living organisms, as well as plants. Finding out about new molecules with a potential biological effect, not yet described in the literature, is ...
Marcin Luczynski, A. Kudelko
semanticscholar +1 more source
Polycyclic aromatic compounds (Print), 2023 We report derivatives of 2,5-disubstituted-1,3,4-oxadiazole as powerful anti-TB and antioxidant compounds. Using substituted aryloxy acetic acids (2a–f) and isoniazid (3) in the presence of phosphorus oxychloride, a series of new 2-(substituted ...
Madhura Datar +4 more
semanticscholar +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Heterocyclic compounds make a very important branch of organic chemistry, and it has always been an interesting area of study in medical chemistry. They are present in a variety of drugs, vitamins and biologically active compounds. Over two decades, 1,
Yu. V. Karpenko +2 more
doaj +1 more source
Activity Profiling of Nitro-Substituted Di(Hetero)Aryl 1,3,4- and 1,2,4-Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential. [PDF]
Arch Pharm (Weinheim)Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Šikorová E +9 more
europepmc +2 more sources
Applied Sciences, 2023 New derivatives of 5-phenyl-1,3,4-oxadiazole substituted at position 2 with (bromomethyl)phenyl or bromoalkyl groups were obtained via microwave-assisted cyclodehydration of unsymmetrical N,N′-diacylhydrazines.
Marcin Łuczyński, Agnieszka Kudelko
doaj +1 more source
Two reaction routes for the preparation of aromatic polyoxadiazoles and polytriazoles: Syntheses and properties [PDF]
, 1994 Two reaction routes for the preparation of aromatic poly-1,3,4-oxadiazoles and poly-1,2,4-triazoles are studied and their influence on the physical properties, i.e., inherent viscosity, glass transition, degradation temperature, and film integrity of the
Boom, J.P. +6 more
core +3 more sources
Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi +1 more
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Therapeutic potential of oxadiazole or furadiazole containing compounds
BMC Chemistry, 2020 As we know that, Oxadiazole or furadi azole ring containing derivatives are an important class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two carbons, one oxygen atom, two nitrogen atoms, and two double bonds is known as ...
Ankit Siwach, Prabhakar Kumar Verma
doaj +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 At the present stage of development of medical chemistry, many basic synthetic approaches to the synthesis of 1,3,4-oxadiazole structures are known, which are focused mainly on the principles of combinatorial chemistry with a wide range of biological ...
Yu. V. Karpenko +2 more
doaj +1 more source