Results 101 to 110 of about 12,547 (208)

Synthesis and Anticancer Activity of 1,3,4-Thiadiazoles with 3-Methoxyphenyl Substituent. [PDF]

Molecules, 2022
Janowska S, Khylyuk D, Gornowicz A, Bielawska A, Janowski M, Czarnomysy R, Bielawski K, Wujec M.   +7 more
europepmc   +1 more source

New derivatives of 2-R1-N-(5-R)-1,3,4-thiadiazol-2-yl-benzolsulfonamides: synthesis, physicochemical properties and biological activity prediction

Annals of Mechnikov's Institute, 2020
Introduction: The analysis of modern literature, including overseas one, showed that a lot of the scientific researches is devoted to finding and creating biologically active compounds on base 1,3,4-thiadiazole.
I Sych, L Perekhoda, Z Іеremina
doaj  

Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E₂ and Leukotriene Biosynthesis Inhibitors. [PDF]

ACS Med Chem Lett, 2023
Potenza M, Giordano A, Chini MG, Saviano A, Kretzer C, Raucci F, Russo M, Lauro G, Terracciano S, Bruno I, Iorizzi M, Hofstetter RK, Pace S, Maione F, Werz O, Bifulco G.   +15 more
europepmc   +1 more source

Synthesis and biological activity of 5-nitrofuran-containing (1,3,4-thiadiazol-2-yl)piperazine moieties as a new type of anti-Helicobacter pylori heterocycles [PDF]

Journal of the Serbian Chemical Society, 2011
In order to find new and potent drug candidates for the treatment of Helicobacter pylori infections‚ in this study attention was focused on the synthesis and anti-H.
ABBAS SHAFIEE, ESKANDAR ALIPOUR, MARYAM OMRANI, MOHSEN VOSOOGHI, FARIDEH SIAVOSHI, MARYAM NAKHJIRI, SAEED EMAMI, SEYED ESMAEIL SADAT-EBRAHIMI, AZADEH YAHYA-MEYMANDI, MOHAMMAD HASSAN MOSHAFI, ALIREZA FOROUMADI   +10 more
doaj  

Synthesis and Biological Activity of 3-(2-Furanyl)-6-Aryl-1,2,4-Triazolo[3,4-b]-1,3,4 –Thiadiazoles

Molecules, 2002
3-(2-Furanyl)-4-amino-5-mercapto-1,2,4-triazole (1) was prepared from 2-furoic acid through a multi-step reaction sequence. Compound 1 reacted with aromatic acids in the presence of phosphorus oxychloride to give 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3,4-b]
Zi-Yi Zhang, Dong-Yong Chen, Xiang-Yun Nan, Xin-Xiang Lei, Xian-Xing Chen, An-Jiang Zhang, Li-Xue Zhang   +6 more
doaj   +1 more source

Design, Synthesis, Antibacterial Evaluations and In Silico Studies of Novel Thiosemicarbazides and 1,3,4-Thiadiazoles. [PDF]

Molecules, 2022
Janowska S, Khylyuk D, Andrzejczuk S, Wujec M.   +3 more
europepmc   +1 more source

Synthesis of 1,3,4-Thiadiazoles: Review

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
Abstract Molecules with 1,3,4-thiadiazole ring structures have potential biological relevance. These organic molecules have potentially reported for their medicinal importance. In this review, different strategies for the synthesis of biologically important molecules of 1,3,4-thiadiazole ring are briefly summarized and an attempt has been made with ...
openaire   +1 more source

Síntese de cristais líquidos fotoluminescentes derivados do heterociclo 1,3,4-Oxadiazol [PDF]

, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemática. Programa de Pós-Graduação em QuímicaA síntese, propriedades fotofísicas e térmicas de duas séries de compostos líquido cristalinos fotoluminescentes
Cristiano, Rodrigo
core  

The Acid and/or Thermal Mediated Ring Contraction of 4H‑1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazoles [PDF]

, 2016
A near-quantitative acid and/or thermal mediated ring contraction of 3′,5′-diarylspiro­(benzo­[d]­[1,3]­dioxole-2,4′-[1,2,6]­thiadiazines) affords 3-aryl-4-(2-arylbenzo­[d]­[1,3]­dioxol-2-yl)-1,2,5-thiadiazoles.
Andreas Kourtellaris (1693780), Panayiotis A. Koutentis (1278807), Andreas S. Kalogirou (1546180)   +2 more
core   +1 more source

New 1,3,4-thiadiazoles as potential anticancer agents: pro-apoptotic, cell cycle arrest, molecular modelling, and ADMET profile. [PDF]

RSC Adv, 2023
Hekal MH, Farag PS, Hemdan MM, El-Sayed AA, Hassaballah AI, El-Sayed WM.   +5 more
europepmc   +1 more source