Results 171 to 180 of about 12,547 (208)

1,3,4-THIADIAZOLES FROM THIOSEMICARBAZIDES

Phosphorus, Sulfur, and Silicon and the Related Elements, 1991
Abstract A new method for the synthesis of 1,3,4-thiadiazoles is described. Thus condensation of 4-methyl-4phenyl-3-thiosemicarbazide with an aldehyde or ketone affords 1,1-disubstituted-6-[1-(arylethylidine) amino] −2,5-dithiobiureas, rather than the anticipated 4,4-disubstituted-3-thiosemicarbazones.
John P. Scovill, Daniel L. Klayman, Judith L. Flippen-anderson, Richard Gilardi   +3 more
openaire   +1 more source

Syntheses of arylsulfonyl‐1,3,4‐thiadiazoles

Journal of Heterocyclic Chemistry, 1996
AbstractReaction of sodium arylsulfinate with 2‐aryl‐5‐chloro‐1,3,4‐thiadiazole gave 2‐aryl‐5‐arylsulfonyl‐1,3,4‐thiadiazole (3) in good yield. Starting from readily available 2‐amino‐5‐benzylmercapto‐1,3,4‐thiadiazole compound 7 was obtained in three steps in moderate yield.
A. Shafiee, A. Foroumadi
openaire   +1 more source

1,3,4-Thiadiazole Based Anticancer Agents

Anti-Cancer Agents in Medicinal Chemistry, 2016
In recent years, researchers like medicinal chemists in the field of medicinal chemistry have widely utilized the 1,3,4-thiadiazole nucleus to investigate its biological and pharmacological effects. This heterocyclic structure has demonstrated various bioactivities such as antifungal, antimicrobial, antiviral, antileishmanial, anti-inflammatory ...
openaire   +2 more sources

2-Amino-5-methyl-1,3,4-thiadiazole and 2-amino-5-ethyl-1,3,4-thiadiazole

Acta Crystallographica Section C Crystal Structure Communications, 2001
The structures of 2-amino-5-methyl-1,3,4-thiadiazole, C(3)H(5)N(3)S, and 2-amino-5-ethyl-1,3,4-thiadiazole, C(4)H(7)N(3)S, have been determined for comparison with unsubstituted 2-amino-1,3,4-thiadiazole. Despite their different space groups (P2(1)/n and Pbca, respectively), the packing modes of the methyl and ethyl derivatives are similar, with ...
openaire   +2 more sources

Synthesis of 1,3,4‐Thiadiazoles from Aldehyde Hydrazones.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Kentaro Okuma, Kazuko Nagakura, Yasutaka Nakajima, Kento Kubo, Kosei Shioji   +4 more
openaire   +1 more source

New Cyclizing Reagent for the Synthesis of 1,3,4-Thiadiazoles

Synthesis, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Vladimir N. Yarovenko, Aleksandr V. Shirokov, Igor V. Zavarzin, Oksana N. Krupinova, Anatolii V. Ignatenko, Mikhail M. Krayushkin   +5 more
openaire   +1 more source

Synthesis of Substituted 1,2,4-Triazoles and 1,3,4-Thiadiazoles

Chemistry of Heterocyclic Compounds, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
T. R. Hovsepian, E. R. Dilanian, A. P. Engoyan, R. G. Melik‐Ohanjanian   +3 more
openaire   +1 more source

Recent Advances in the Chemistry of 1,3,4-Thiadiazoles

1968
Publisher Summary This chapter discusses homologs, functional groups, physical properties, and the uses of 1, 3, 4-thiadiazole. The development of 1, 3, 5- thiadiazole chemistry is linked to the discovery of phenylhydrazine and hydrazine. The numbering of the 1, 3, 4-thiadiazole ring follows from 1.
openaire   +2 more sources

A new synthesis of symmetrical 2,5‐diaryl‐1,3,4‐thiadiazoles

Journal of Heterocyclic Chemistry, 1983
AbstractTreatment of aromatic aldehydes with sulfur and hydrazine hydrate in the ratio 1:2:3, respectively, under the Willgerodt conditions affords the title compounds in excellent yields and in a good state of purity. Under the same conditions 2‐chloro and 2,6‐dichlorobenzaldehyde yield 3H‐1,2‐benzodithiole‐3‐thione and bis‐(2,6‐dichlorobenzyl ...
G. Mazzone, PUGLISI, Giovanni, F. Bonina, A. Corsaro   +3 more
openaire   +3 more sources

ChemInform Abstract: Utilization of 2‐Halo‐1,3,4‐thiadiazoles in the Synthesis of 2‐Functionalized 1,3,4‐Thiadiazole Derivatives.

ChemInform, 2011
AbstractNovel 2‐halo‐5‐aryloxymethyl‐thiadiazoles (II) are prepared by diazotization of aminothiadiazoles (I) in the presence of an acid‐catalyst under copper‐free conditions.
Xi‐Cun Wang, Jin‐Ge Luo, Xiao‐Mei Ding, Zheng‐Jun Quan   +3 more
openaire   +1 more source