Results 151 to 160 of about 12,547 (208)
Design, synthesis, and antiproliferative activity of novel thiazole-based derivatives as tubulin polymerization inhibitors targeting the colchicine binding site. [PDF]
Al-Wahaibi LH +6 more
europepmc +1 more source
Hydrazides as Powerful Tools in Medicinal Chemistry: Synthesis, Reactivity, and Biological Applications. [PDF]
Teixeira S +2 more
europepmc +1 more source
Synthesis and Bioactivity Studies of Benzimidazole-Chalcone Hybrids. [PDF]
Makgoathana HD +4 more
europepmc +1 more source
Benzo[<i>d</i>]imidazole anchored oxadiazole derivatives: synthesis, characterization, biological evaluation, <i>in silico</i> docking and ADME-T analysis. [PDF]
Salluri YR, Chepuri K, Anwar S.
europepmc +1 more source
Azodicarboxylates: valuable reagents for the multicomponent synthesis of novel 1,3,4-thiadiazoles and imidazo[2,1-b][1,3,4]thiadiazoles [PDF]
Abstract Upon reaction of 4,5-disubstituted-N-arylaminoimidazole-2-thiones with isocyanides in the presence of azodicarboxylates (1.2 equiv) at rt, the imidazo[2,1-b][1,3,4]thiadiazoles were formed as the only reaction products in very good yields, whereas by using higher reaction temperatures, along with the imidazo[2,1-b][1,3,4]thiadiazoles, the ...
Tryfon Zarganes-Tzitzikas +2 more
exaly +4 more sources
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Chemotherapy, 2009
Nine 1,3,4-thiadiazoles showed an antiviral action against Mengo virus; four of them were also active against vaccinia virus and one against fowl plague virus. Investigations with Mengo virus revealed plaque reduction, inhibition of the cytopathic effect and depression of virus multiplication, with the maximum activity after substance addition from 0–2
Marion Tonew, Elke Klimke
openaire +2 more sources
Nine 1,3,4-thiadiazoles showed an antiviral action against Mengo virus; four of them were also active against vaccinia virus and one against fowl plague virus. Investigations with Mengo virus revealed plaque reduction, inhibition of the cytopathic effect and depression of virus multiplication, with the maximum activity after substance addition from 0–2
Marion Tonew, Elke Klimke
openaire +2 more sources
Synthesis and Reactions of Novel 2,5-Disubstituted 1,3,4-Thiadiazoles [PDF]
The desired 1,3,4-thiadiazole compounds bearing different substituents were obtained by the cyclization of the corresponding thiosemicarbazide followed by the reaction with electrophilic reagents, such as aromatic aldehydes, isatin, phenyl isothiocyanate,
Mahmoud R Mahmoud +2 more
exaly +2 more sources
Journal of Molecular Spectroscopy, 1962
Abstract The microwave spectra of 1, 3, 4-thiadiazole (I) and [ 34 S] 1, 3, 4-thiadiazole (II) have been recorded in the 15,000–30,000 Mc/sec region. Twelve and ten transitions, respectively, were assigned. The rotational constants of (I) are, A = 8907.51 ± 0.10, B = 5569.27 ± 0.02, and C = 3424.80 ± 0.03 Mc/sec. For (II), A = 8908.15 ± 0.20,
Børge Bak +4 more
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Abstract The microwave spectra of 1, 3, 4-thiadiazole (I) and [ 34 S] 1, 3, 4-thiadiazole (II) have been recorded in the 15,000–30,000 Mc/sec region. Twelve and ten transitions, respectively, were assigned. The rotational constants of (I) are, A = 8907.51 ± 0.10, B = 5569.27 ± 0.02, and C = 3424.80 ± 0.03 Mc/sec. For (II), A = 8908.15 ± 0.20,
Børge Bak +4 more
openaire +1 more source

