Results 81 to 90 of about 3,168 (197)

Synthesis and Antimicrobial Activity of Some New Thiadiazoles, Thioamides, 5-Arylazothiazoles and Pyrimido[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines

Molecules, 2016
A novel series of 1,3,4-thiadiazoles, 5-arylazothiazoles and hexahydropyrimido-[4,5-d][1,2,4]triazolo[4,3-a]pyrimidines were synthesized via reaction of hydrazonoyl halides with each of alkyl carbothioates, carbothioamides and 7-thioxo-5,6,7,8 ...
Abdou O. Abdelhamid, Ibrahim E. El Sayed, Mohamed Z. Hussein, Mangoud M. Mangoud   +3 more
doaj   +1 more source

1,3,4-Thiadiazole-Containing Azo Dyes: Synthesis, Spectroscopic Properties and Molecular Structure

Molecules, 2020
Three series of azo dyes derived from 2-amino-5-aryl-1,3,4-thiadiazoles and aniline, N,N-dimethylaniline and phenol were synthesized in high yields by a conventional diazotization-coupling sequence.
Agnieszka Kudelko, Monika Olesiejuk, Marcin Luczynski, Marcin Swiatkowski, Tomasz Sieranski, Rafal Kruszynski   +5 more
doaj   +1 more source

Synthesis of Mesoionic 1,3,4-thiadiazoles

, 1968
Synthesis of Mesoionic 1,3,4 ...
P. B. Talukdar, S. K. Sengupta
openaire   +1 more source

Synthesis of Novel Thiazole/Thiadiazole Conjugates of Fluoroquinolones as Potent Antibacterial and Antimycobacterial Agents

Chemical Biology &Drug Design, Volume 105, Issue 5, May 2025.
Twenty new fluoroquinolone‐azole conjugates were synthesized. The synthesized compounds were screened vs. various bacterial and mycobacterial strains. Most of the compounds showed potent antibacterial activity. Compound 35 was equipotent with ciprofloxacin vs. M. tuberculosis H37Rv.
Pınar Poyraz Yılmaz, Necla Kulabaş, Arif Bozdeveci, Siva Krishna Vagolu, Mohd Imran, Esra Tatar, Şengül Alpay Karaoğlu, Dharmarajan Sriram, Ammar A. Razzak Mahmood, İlkay Küçükgüzel   +9 more
wiley   +1 more source

Some Biological Applications and Mechanistic Insights of Benzaldehyde‐Substituted Thiosemicarbazones and Their Metal Complexes: A Review

Natural Sciences, Volume 5, Issue 1-2, April 2025.
ABSTRACT Thiosemicarbazones (TSCs) and their metal complexes have been subjected to study over several decades. Their medicinal importance as anticancer, antioxidant, antimicrobial, and antidiabetic has been explored. Continual efforts have been made toward activity enhancement that can be achieved by making suitable structural alterations or by ...
Ekhlakh Veg, Kulsum Hashmi, Mohammad Imran Ahmad, Seema Joshi, Abdul Rahman Khan, Tahmeena Khan   +5 more
wiley   +1 more source

Synthesis and Preliminary Antimicrobial Study of 2-Amino-5-Mercapto-1,3,4-Thiadiazole Derivatives

Iraqi Journal of Pharmaceutical Sciences, 2017
Nitrogen heterocycles are of a special interest because they constitute an important class of natural and non natural products, many of which exhibit useful biological activities.Among these nitrogen heterocycles are 1, 3, 4-thiadiazole containing ...
Husam A. Ameen, Ahlam J. Qasir
doaj   +3 more sources

Sulfonamide‐Bearing Pyrazolone Derivatives as Multitarget Therapeutic Agents: Design, Synthesis, Characterization, Biological Evaluation, In Silico ADME/T Profiling and Molecular Docking Study

Pharmacology Research &Perspectives, Volume 13, Issue 2, April 2025.
ABSTRACT The research and design of new inhibitors for the treatment of diseases such as Alzheimer's disease and glaucoma through inhibition of cholinesterases (ChEs; acetylcholinesterase, AChE and butyrylcholinesterase, BChE) and carbonic anhydrase enzymes are among the important targets.
Nebih Lolak, Suleyman Akocak, Meryem Topal, Ümit Muhammet Koçyiğit, Mesut Işık, Cüneyt Türkeş, Fevzi Topal, Mustafa Durgun, Şükrü Beydemir   +8 more
wiley   +1 more source

Biological Potential of Substituted Thiadiazole Compounds [PDF]

, 2015
Heterocyclic compounds are present in most biologically active molecules. The chemistry of heterocyclic compounds has been an interesting field of study.
Asif, Mohammad
core  

1,3,4-Thiadiazoles and 1,3-thiazoles from one-pot reaction of bisthioureas with 2-(bis(methylthio)methylene)malononitrile and ethyl 2-cyano-3,3-bis(methylthio)acrylate [PDF]

, 2016
Bisthioureas reacted with either 2-(bis(methylthio)methylene)malononitrile or ethyl 2-cyano-3,3-bis(methylthio)acrylate to give 1,3,4-thiadiazoles and 1,3-thiazoles.
Abd Al-Latif, El-Shimaa S. M., Aly, Ashraf A., Bräse, Stefan, Hassan, Alaa A., Ibrahim, Mahmoud A. A., Nieger, Martin, Spuling, Eduard   +6 more
core   +2 more sources

2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents

Drug Design, Development and Therapy, 2018
Georgeta Serban,1,* Oana Stanasel,2,* Eugenia Serban,3 Sanda Bota2,* 1Pharmaceutical Chemistry Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania; 2Chemistry Department, Faculty of Sciences, University of Oradea, Oradea,
Serban G, Stanasel O, Serban E, Bota S
doaj