Results 81 to 90 of about 1,311 (155)

2-Amino-1,3,4-thiadiazoles as Glutaminyl Cyclases Inhibitors Increase Phagocytosis through Modification of CD47-SIRPα Checkpoint. [PDF]

ACS Med Chem Lett, 2022
Park E, Song KH, Kim D, Lee M, Van Manh N, Kim H, Hong KB, Lee J, Song JY, Kang S.   +9 more
europepmc   +1 more source

Synthesis and Preliminary Anticancer Activity Assessment of N-Glycosides of 2-Amino-1,3,4-thiadiazoles. [PDF]

Molecules, 2021
Żurawska K, Stokowy M, Kapica P, Olesiejuk M, Kudelko A, Papaj K, Skonieczna M, Szeja W, Walczak K, Kasprzycka A.   +9 more
europepmc   +1 more source

5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

Drug Design, Development and Therapy, 2018
Sobhi M Gomha,1 Mastoura M Edrees,2,3 Zeinab A Muhammad,2 Ahmed AM El-Reedy4 1Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt; 2Department of Organic Chemistry, National Organization for Drug Control and Research (NODCAR ...
Gomha SM, Edrees MM, Muhammad ZA, El-Reedy AA   +3 more
doaj  

Synthesis of 1,3,4-Thiadiazoles: Review

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
Abstract Molecules with 1,3,4-thiadiazole ring structures have potential biological relevance. These organic molecules have potentially reported for their medicinal importance. In this review, different strategies for the synthesis of biologically important molecules of 1,3,4-thiadiazole ring are briefly summarized and an attempt has been made with ...
openaire   +1 more source

Green synthesis of novel coumarin derivatives via grinding approach and their antimicrobial evaluation

Green Chemistry Letters and Reviews
Herein, a rapid, clean, less expensive and environmentally friendly route to a novel series of coumarins bearing thiazoles or 1,3,4-thiadiazoles was developed via grinding method under solvent conditions.
Anhar Abdel-Aziem
doaj   +1 more source

In vitro and in silico insights into antimicrobial and anticancer activities of novel imidazo[2,1-b][1,3,4]thiadiazoles. [PDF]

Sci Rep
Dwarakanath D, Nayak YN, Kulal A, Pandey S, Pai KSR, Gaonkar SL.   +5 more
europepmc   +1 more source

Design, synthesis and biological evaluation of non-glucosidal based 1,3,4-thiadiazoles as SGLT-2 inhibitors. [PDF]

Future Med Chem
Sharma S, Kumar S, Gupta J, Mittal A, Khurana N.   +4 more
europepmc   +1 more source

Future Prospects in the Treatment of Parasitic Diseases: 2-Amino-1,3,4-Thiadiazoles in Leishmaniasis. [PDF]

Molecules, 2019
Serban G.
europepmc   +1 more source

Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity. [PDF]

Sci Rep
Abdel-Aziem A, Abdelhamid AO.
europepmc   +1 more source

Assessment of the Microbiological Potential and Spectroscopic Properties of New Imino-1,3,4-Thiadiazoles Showing the ESIPT Effect Strongly Enhanced by Aggregation. [PDF]

Molecules
Chruściel E, Ślusarczyk L, Gładyszewska B, Karcz D, Luchowski R, Nucia A, Ociepa T, Nowak M, Kowalczyk K, Włodarczyk A, Gagoś M, Okoń S, Matwijczuk A.   +12 more
europepmc   +1 more source