Results 61 to 70 of about 14,599 (204)
Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies
ChemMedChem, Volume 21, Issue 16, 27 August 2026.A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga +5 more
wiley +1 more source
Synthesis and characterization of 1,2,4-triazolo-1,3,4-thiadiazoles [PDF]
, 2022 In this project, a 1,2,4-triazole and eight 1,2,4-triazolo-1,3,4-thiadiazole derivatives have been successfully synthesized and characterized. On the other hand, 1,2,4-triazolo-1,3,4-thiadiazoles were synthesized through refluxing 1,2,4-triazole and ...
Loo, Xin Tong
core
An Integrated DNA Nanoprobe for Intranuclear Imaging and In Situ Profiling of OGG1 Activity
Advanced Science, Volume 13, Issue 47, 24 August 2026.The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
Aggregate, Volume 7, Issue 8, August 2026.The noncovalent conformational locks (NoCLs) strategy modulates molecular aggregation to synergistically enhance NIR‐II absorption, NIR‐IIb emission, and photothermal conversion efficiency (PCE). QCF NPs incorporating both S···O and S···N NoCLs achieve concurrent NIR‐IIb emission (1550 nm) and PCE (75%) under low‐power 1064 nm excitation, establishing ...
Xin Chen +7 more
wiley +1 more source
BMC Chemistry, 2019 Background Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores with a wide range of biological ...
Abdou O. Abdelhamid +5 more
doaj +1 more source
We report a method for using elemental sulfur to facilitate the cyclization of aryl hydrazones and aryl isothiocyanates, affording biorelated 2-imino-1,3,4-thiadiazoles.
Anh T. Nguyen (7865891) +4 more
core +1 more source
Synthesis and in vitro antibacterial activity evaluation of coumarin-1,3,4-thiadiazoles hybrids [PDF]
Purpose: Hybridization of two or more potent pharmacophores into a single molecule is one of the current strategies to synthesize compounds with improved pharmacological activity.
Asrat, Ergena
core +1 more source
Archiv der Pharmazie, Volume 359, Issue 8, August 2026.This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan +2 more
wiley +1 more source