Diastereoselective Three-Component 1,3-Dipolar Cycloaddition to Access Functionalized β-Tetrahydrocarboline- and Tetrahydroisoquinoline-Fused Spirooxindoles [PDF]
MoleculesA chemselective catalyst-free three-component 1,3-dipolar cycloaddition has been described. The unique polycyclic THPI and THIQs were creatively employed as dipolarophiles, which led to the formation of functionalized β-tetrahydrocarboline- and ...
Yongchao Wang +8 more
doaj +2 more sources
Synthesis of Spiroisoxazolines by 1,3-Dipolar Cycloaddition [PDF]
Molecules, 1997 The cycloaddition of the chiral nitrile oxide 1 to 1-R-substituted 3,3-methylene-5,5-dimethyl-2-pyrrolidinones 2 (where R is H, n-butyl-, 1,1-dimethylethoxycarbonyl-, 1-methylethenyl- and acetyl-) proceeds regioselectively under the formation of ...
Peter Ertl +3 more
doaj +3 more sources
Enzymatic control of cycloadduct conformation ensures reversible 1,3 dipolar cycloaddition in a prFMN dependent decarboxylase [PDF]
Nat Chem, 2019 The UbiD enzyme plays an important role in bacterial ubiquinone (coenzyme Q) biosynthesis. It belongs to a family of reversible decarboxylases that interconvert propenoic or aromatic acids with the corresponding alkenes or aromatic compounds using a ...
S. Bailey +8 more
semanticscholar +2 more sources
3-Benzoylisoxazolines by 1,3-Dipolar Cycloaddition: Chloramine-T-Catalyzed Condensation of α-Nitroketones with Dipolarophiles [PDF]
Molecules, 2021 In this study, 3-benzoylisoxazolines were synthesized by reacting alkenes with various α-nitroketones using chloramine-T as the base. The scope of α-nitroketones and alkenes is extensive, including different alkenes and alkynes to form various ...
Xinhui Pan +8 more
doaj +2 more sources
Understanding the 1,3‐Dipolar Cycloadditions of Allenes [PDF]
Chemistry – A European Journal, 2020 AbstractWe have quantum chemically studied the reactivity, site‐, and regioselectivity of the 1,3‐dipolar cycloaddition between methyl azide and various allenes, including the archetypal allene propadiene, heteroallenes, and cyclic allenes, by using density functional theory (DFT).
Kevin van Dommelen +5 more
openaire +5 more sources
An Overlooked Pathway in 1,3‐Dipolar Cycloadditions of Diazoalkanes with Enamines [PDF]
Angewandte Chemie International Edition, 2022 AbstractMethyl diazoacetate reacts with 1‐(N‐pyrrolidino)cycloalkenes to give products of 1,3‐dipolar cycloadditions and azo couplings. The kinetics and mechanisms of these reactions were investigated by NMR spectroscopy and DFT calculations. Orthogonal π‐systems in the 1,3‐dipoles of the propargyl‐allenyl type allow for two separate reaction pathways ...
Le Li +5 more
openaire +3 more sources
1,3-Dipolar cycloadditions of acridine with nitrile oxides [PDF]
Arkivoc, 2002 Siteand regio-isomeric mono-cycloadducts 9 are formed in the reactions of mesito1b and dichloromesitonitrile oxide 1c with acridine 6 in a 1:2 ratio, while the reaction of 1b and 6 in a 10:1 ratio afforded, besides the mono-cycloadduct 9b and traces of the corresponding oxime 10b, the bis-cycloadduct 12 with the opposite regiochemistry to that of the ...
CORSARO, Antonino +5 more
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Triazole-oligomers by 1,3-dipolar cycloaddition [PDF]
ARKIVOC, 2006 A variety of triazole-oligomers have been prepared under microwave and conventional conditions from novel alkynes and azides.
Alan R. Katritzky +8 more
doaj +3 more sources
Dynamic Catalytic Highly Enantioselective 1,3‐Dipolar Cycloadditions [PDF]
Angewandte Chemie International Edition, 2021 AbstractIn dynamic covalent chemistry, reactions follow a thermodynamically controlled pathway through equilibria. Reversible covalent‐bond formation and breaking in a dynamic process enables the interconversion of products formed under kinetic control to thermodynamically more stable isomers.
Herbert Waldmann +9 more
openaire +6 more sources
ChemInform Abstract: Iridium‐Catalyzed 1,3‐Dipolar Cycloadditions [PDF]
ChemInform, 2010 AbstractReview: 47 refs.
Carmona, Daniel, Oro, Luis A.
openaire +4 more sources