Results 51 to 60 of about 5,065 (202)

Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Molecules, 2010
Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively.
Kohzo Yoshida, Tsubasa Inokuma, Kiyosei Takasu, Yoshiji Takemoto   +3 more
doaj   +1 more source

Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes [PDF]

, 2017
The Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may ...
Agrofoglio, Luigi A., Collina, Simona, Guillou, Catherine, Gütschow, Michael, Hulme, Christopher, Karaman, Rafik, Kokotos, George, Liu, Hong, Luque Garriga, F. Xavier, Mangoni, Arduino A., Muñoz-Torrero López-Ibarra, Diego, Prokai-Tatrai, Katalin, Ragno, Rino, Rautio, Jarkko, Sabatier, Jean-Marc, Siciliano, Carlo, Sousa, Maria Emília de   +16 more
core   +4 more sources

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

Transfer hydrosilylation [PDF]

, 2016
Transfer hydrogenation is without question a common technology in industry and academia. Unlike its countless varieties, conceptually related transfer hydrosilylations had essentially been unreported until the recent development of a radical and an ionic
Oestreich, Martin
core   +1 more source

The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis

Angewandte Chemie International Edition, EarlyView.
Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio, René Slot Bitsch, Karl Anker Jørgensen   +2 more
wiley   +1 more source

Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1997
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei, Karim Akbari Dilmaghani   +1 more
doaj  

A low-voltage activated, transient calcium current is responsible for the time-dependent depolarizing inward rectification of rat neocortical neurons in vitro [PDF]

, 1987
Intracellular recordings were obtained from rat neocortical neurons in vitro. The current-voltage-relationship of the neuronal membrane was investigated using current- and single-electrode-voltage-clamp techniques.
A Constanti, A Constanti, A Finkelstein, BA Vogt, Bernd Sutor, BW Connors, CE Stafstrom, CE Stafstrom, CE Stafstrom, CE Stafstrom, D Johnston, DA McCormick, E Carbone, F Crepel, H Jahnsen, H Jahnsen, H Jahnsen, H Jahnsen, JR Hotson, JR Howe, JR Howe, JV Halliwell, K Murase, ML Mayer, P Adams, P Franz, P Schwindt, PG Nelson, R Llin�s, R Llin�s, R Llin�s, R Llin�s, RJ Docherty, S Hagiwara, SA Fedulova, W Rall, W Rall, Walter Zieglg�nsberger   +37 more
core   +1 more source

Organophotoredox/Cobalt‐Catalyzed Retro‐Hydroformylation of Aldehydes

ChemistryEurope, EarlyView.
A new photoredox/cobalt retro‐hydroformylation is developed. This one‐pot two‐step process involves the in situ formation of the corresponding 1,4‐dihydropyridine as key intermediate. Under mild reaction conditions, alkenes are efficiently produced from a wide range of aliphatic α‐monosubstituted aldehydes, with high functional‐group tolerance.
Augustin Nouaille, Emmanuel Magnier, Corinne Gosmini, Guillaume Dagousset   +3 more
wiley   +1 more source

1,4-Dihydropyridines: Reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ABTS radical cation [PDF]

, 2004
In the present paper, a direct quenching of radical species by a number of synthesized nitrosoaryl 1,4-dihydropyridines and their parent nitroaryl 1,4-dihydropyridines was determined in aqueous media at pH 7.4. These two series of compounds were compared
Camargo Grandón, Rodrigo, López Alarcón, Camilo, Núñez Vergara, Luis, Santander, P., Squella Serrano, Juan, Valenzuela, V.   +5 more
core   +1 more source

Conformation of 1,4‐dihydropyridine — planar or boat‐like? [PDF]

FEBS Letters, 1988
The geometry of the 1,4‐dihydropyridine molecule was completely optimized employing three different ab initio basis sets (6–31 G*, 4–31 G, STO—3G). The most reliable 6–31G* basis set provides a very flat boat conformation which may easily undergo defolding to a planar ring arrangement.
H. Hofmann, CIMIRAGLIA, Renzo
openaire   +2 more sources