Results 121 to 130 of about 12,036 (214)

Serum contents of endocannabinoids are correlated with blood pressure in depressed women

Lipids in Health and Disease, 2012
Background Depression is known to be a risk factor for cardiovascular diseases but the underlying mechanisms remain unclear. Since recent preclinical evidence suggests that endogenous agonists of cannabinoid receptors (endocannabinoids) are involved in ...
Ho WS Vanessa, Hill Matthew N, Miller Gregory E, Gorzalka Boris B, Hillard Cecilia J   +4 more
doaj   +1 more source

Potential of Endocannabinoids to Control Bladder Pain

Frontiers in Systems Neuroscience, 2018
Bladder-related pain is one of the most common forms of visceral pain, and visceral pain is among the most common complaints for which patients seek physician consultation. Despite extensive studies of visceral innervation and treatment of visceral pain,
Dale E. Bjorling, Zun-yi Wang
doaj   +1 more source

Inhibiting degradation of 2-arachidonoylglycerol as a therapeutic strategy for neurodegenerative diseases. [PDF]

Pharmacol Ther, 2023
Chen C.
europepmc   +1 more source

Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents

The Journal of Headache and Pain
Background Increasing endocannabinoids (endoCBs), anandamide (AEA) and 2-arachidonoylglycerol (2-AG), through inhibition of the degrading hydrolase enzymes, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively, has been ...
Georgii Krivoshein, Adriana Della Pietra, Juha Savinainen, Arn M. J. M. van den Maagdenberg, Rashid Giniatullin   +4 more
doaj   +1 more source

Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

Journal of Neuroinflammation, 2019
Background Palmitoylethanolamide (PEA) is a pleiotropic endogenous lipid mediator currently used as a “dietary food for special medical purposes” against neuropathic pain and neuro-inflammatory conditions.
Stefania Petrosino, Aniello Schiano Moriello, Roberta Verde, Marco Allarà, Roberta Imperatore, Alessia Ligresti, Ali Mokhtar Mahmoud, Alessio Filippo Peritore, Fabio Arturo Iannotti, Vincenzo Di Marzo   +9 more
doaj   +1 more source

Striatonigral direct pathway 2-arachidonoylglycerol contributes to ethanol effects on synaptic transmission and behavior. [PDF]

Neuropsychopharmacology, 2023
Augustin SM, Gracias AL, Luo G, Anumola RC, Lovinger DM.   +4 more
europepmc   +1 more source

Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina. [PDF]

Int J Mol Sci, 2023
Papadogkonaki S, Spyridakos D, Lapokonstantaki E, Chaniotakis N, Makriyannis A, Malamas MS, Thermos K.   +6 more
europepmc   +1 more source

Critical role of the endocannabinoid system in mediating rapid glucocorticoid effects on memory for emotionally arousing experiences

European Journal of Psychotraumatology, 2012
Rationale : There is extensive evidence that glucocorticoid hormones impair the retrieval of memory of emotionally arousing experiences. Although it is known that glucocorticoid effects on memory retrieval impairment depend on rapid interactions with ...
Benno Roozendaal
doaj   +1 more source

Effects of acute cannabidiol on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice

Frontiers in Neuroscience
BackgroundSome evidence suggests that cannabidiol (CBD) has potential to help alleviate HIV symptoms due to its antioxidant and anti-inflammatory properties.
Barkha J. Yadav-Samudrala, Benjamin L. Gorman, Karenna M. Barmada, Havilah P. Ravula, Caitlin J. Huguely, E. Diane Wallace, Michelle R. Peace, Justin L. Poklis, Wei Jiang, Wei Jiang, Sylvia Fitting   +10 more
doaj   +1 more source

Inhibition of 2-arachidonoylglycerol degradation enhances glial immunity by single-cell transcriptomic analysis. [PDF]

J Neuroinflammation, 2023
Zhu D, Zhang J, Hashem J, Gao F, Chen C.
europepmc   +1 more source