Results 111 to 120 of about 12,036 (214)

Inactivation of anandamide signaling : A continuing Debate [PDF]

open access: yes, 2010
Copyright 2011 Elsevier B.V., All rights reserved.Peer reviewedPublisher ...
Ahluwalia   +106 more
core   +3 more sources

Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity [PDF]

open access: yes, 2017
Aims Aim of this study was to evaluate a possible association between endocannabinoid (EC) plasma levels, such as anandamide (AEA) and 2-arachidonoylglycerol (2-AG), and coronary circulatory function in obesity. Methods and results Myocardial blood flow (
Carballo, Sebastian   +15 more
core  

Elevated Brain Cannabinoid CB1 Receptor Availability in Posttraumatic Stress Disorder: A Positron Emission Tomography Study [PDF]

open access: yes, 2014
Endocannabinoids and their attending cannabinoid type 1 receptor (CB1) have been implicated in animal models of posttraumatic stress disorder (PTSD). However, their specific role has not been studied in people with PTSD.
Bailey, Christopher R.   +14 more
core   +1 more source

Az endokannabinoid jelátviteli útvonal molekuláris sokfélesége és plaszticitása agykérgi szinapszisokban = Molecular diversity and plasticity of endocannabinoid signaling at cortical synapses [PDF]

open access: yes, 2011
Az OTKA-NNF 78918 pályázat támogatásával számos kérgi területen tártuk fel a diacil-glicerol lipáz (DGL)-alfa, a legfontosabb endokannabinoid-szintetizáló enzim, valamint a monoacil-glicerol lipáz (MGL), a fő endokannabinoid-lebontó enzim, illetve a CB1 ...
Katona, István   +2 more
core  

Bidirectional regulation of endocannabinoid signaling in the amygdala contributes to activation and adaptation of the stress response

open access: yesEuropean Journal of Psychotraumatology, 2012
Rationale : Endocannabinoids have been shown to be important for the regulation of multiple aspects of the stress response, although the neural circuits underlying this phenomenon are not well characterized.
Matthew N. Hill
doaj   +1 more source

Endogenous Cannabinoids in Crohn’s Disease

open access: yesApplied Sciences
Background: An increasing number of people around the world suffer from Crohn’s disease (CD), one of the inflammatory bowel diseases (IBDs). Recent evidence suggests that the endogenous cannabinoid system plays an important role in IBD.
Michał S. Bochenek   +3 more
doaj   +1 more source

A novel activity of microsomal epoxide hydrolase: metabolism of the endocannabinoid 2-arachidonoylglycerol

open access: yesJournal of Lipid Research, 2014
Microsomal epoxide hydrolase (EPHX1, EC 3.3.2.9) is a highly abundant α/β-hydrolase enzyme that is known for its catalytical epoxide hydrolase activity.
Kasem Nithipatikom   +4 more
doaj   +1 more source

Stimulatory and Inhibitory Roles of Brain 2-Arachidonoylglycerol in Bombesin-Induced Central Activation of Adrenomedullary Outflow in Rats

open access: yesJournal of Pharmacological Sciences, 2013
2-Arachidonoylglycerol (2-AG) is recognized as a potent endocannabinoid, which reduces synaptic transmission through cannabinoid CB1 receptors, and is hydrolyzed by monoacylglycerol lipase (MGL) to arachidonic acid (AA), a cyclooxygenase substrate.
Takahiro Shimizu   +2 more
doaj   +1 more source

Increasing endogenous 2‐arachidonoylglycerol levels counteracts colitis and related systemic inflammation

open access: yesThe FASEB Journal, 2011
ABSTRACT Inflammatory bowel diseases (IBDs) are chronic inflammatory conditions for which new therapeutic approaches are needed. Genetic and pharmacological data point to a protective role of CB 1 and CB 2
Al Houayek, Mireille   +4 more
openaire   +3 more sources

Obesity and sleep disturbance: the chicken or the egg? [PDF]

open access: yes, 2018
Epidemiological studies suggested an association between obesity and sleep disturbances. Obstructive sleep apnea is the most prevalent type of obesity-related sleep disorder that lead to an increased risk for numerous chronic health conditions.
Annunziata, G   +6 more
core   +1 more source

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