Results 111 to 120 of about 24,579,074 (168)

Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration

, 2001
Endogenous cannabinoid receptor ligands (endocannabinoids) may rescue neurons from glutamate excitotoxicity. As these substances also accumulate in cultured immature neurons following neuronal damage, elevated endocannabinoid concentrations may be ...
Patricia C. Schmid, Javier Fernández-Ruiz, J., Henrik H. Hansen, Manzanares, J., Schmid, P.C., Bittigau, P., Isabel Lastres‐Becker, Hansen, H.H., Petra Bittigau, Harald S. Hansen, Lastres-Becker, I., Fernando Berrendero, Schmid, H.H.O., Jorge Manzanares, Hansen, Harald S., Harald H. O. Schmid, Chrysanthy Ikonomidou, Ikonomidou, C., Berrendero, F., J. Javier Fernández‐Ruiz   +19 more
core   +1 more source

2-Arachidonoylglycerol-mediated endocannabinoid signaling modulates mechanical hypersensitivity associated with alcohol withdrawal in mice. [PDF]

Alcohol Clin Exp Res, 2022
Morgan A, Adank D, Johnson K, Butler E, Patel S.   +4 more
europepmc   +1 more source

Differential inhibitory effects of endocannabinoids on neuronal firing of mouse meningeal afferents

The Journal of Headache and Pain
Background Increasing endocannabinoids (endoCBs), anandamide (AEA) and 2-arachidonoylglycerol (2-AG), through inhibition of the degrading hydrolase enzymes, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively, has been ...
Georgii Krivoshein, Adriana Della Pietra, Juha Savinainen, Arn M. J. M. van den Maagdenberg, Rashid Giniatullin   +4 more
doaj   +1 more source

Augmentation of 2-arachidonoylglycerol signaling in astrocytes maintains synaptic functionality by regulation of miRNA-30b. [PDF]

Exp Neurol, 2023
Zhu D, Zhang J, Gao F, Hu M, Hashem J, Chen C.   +5 more
europepmc   +1 more source

2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes

, 2017
Several studies have linked impaired glucose uptake and insulin resistance (IR) to functional impairment of the heart. Recently, endocannabinoids have been implicated in cardiovascular disease. However, the mechanisms involving endocannabinoid signaling,
Joost J. F.P. Luiken, Glatz, Jan F. C., Chanda, Dipanjan, Miranda Nabben, Neumann, Dietbert, Neumann, Dietbert; id_orcid, Yilin Liu, Will Coumans, Jan F.C. Glatz, Zhu, Xiaoqing, Nabben, Miranda, Coumans, Will, Oligschlaeger, Yvonne, Dipanjan Chanda, Dietbert Neumann, Luiken, Joost J. F. P., Xiaoqing Zhu, Nabben, Miranda; id_orcid, Liu, Yilin, Li, Jieyi, Geraets, Ilvy, Yvonne Oligschlaeger, Ilvy Geraets, Jieyi Li   +23 more
core   +1 more source

Preparation of 2-Arachidonoylglycerol by Enzymatic Alcoholysis: Effects of Solvent and Water Activity on Acyl Migration. [PDF]

Foods, 2022
Wang X, Liu K, Wang Y, Huang Z, Wang X.
europepmc   +1 more source

Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol. [PDF]

J Cardiovasc Transl Res, 2023
Avraamidou E, Nöthel M, Danisch M, Bindila L, Schmidt SV, Lutz B, Nickenig G, Jehle J.   +7 more
europepmc   +1 more source

Identifying Potential Human Monoacylglycerol Lipase Inhibitors from the Phytoconstituents of Morinda Citrifolia L. Fruits by in silico Pharmacology and in vitro Study

Journal of Experimental Pharmacology
Asman Sadino,1,2,* Nyi Mekar Saptarini,3 Jutti Levita,4,* Dwi Syah Fitra Ramadhan,5 Adryan Fristiohady,6 Supat Jiranusornkul7 1Doctoral Program in Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia ...
Sadino A, Saptarini NM, Levita J, Ramadhan DSF, Fristiohady A, Jiranusornkul S   +5 more
doaj  

The Endocannabinoid 2-Arachidonoylglycerol Bidirectionally Modulates Acute and Protracted Effects of Predator Odor Exposure. [PDF]

Biol Psychiatry, 2022
Kondev V, Morgan A, Najeed M, Winters ND, Kingsley PJ, Marnett L, Patel S.   +6 more
europepmc   +1 more source

Attenuation of allodynia and microglial reactivity by inhibiting the degradation of 2-arachidonoylglycerol following injury to the trigeminal nerve in mice. [PDF]

Heliyon, 2022
Kamimura R, Hossain MZ, Takahashi K, Saito I, Kitagawa J.   +4 more
europepmc   +1 more source